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B&J NSAIDs > IL2 or IL6 Receptor Antagonist > Flashcards

IL2 or IL6 Receptor Antagonist Flashcards

0
Q

Tocilizumab

A

Actemra
Binds to IL6 receptor and competitive inhibits
6

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1
Q

Anakira

A

Kineret
Blocks IL6 by competitive inhibition
Blocks pain, degradation and bone resorption

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2
Q

Abatacept

A

Orencia
Fusion: CTLA4 and Fc
Fc binds to CD28 and blocks interaction with T cell
MHC thinks it is self and initiates T cell anergy

Anti-Costimulation

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3
Q

Rituximab

A

Rituxan
Binds to B cell CD20 and blocks
Decreases B cells as APC, secreted cytokines, rheumatoid factor
AntiCD20

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4
Q

AntiCD20

A

Ofatumumab

Ocrelizumab

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B&J NSAIDs (4 decks)

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