IHCs Flashcards
1
Q
CD1a (2)
A
- Immature T cells (common thymocytes)
- Langerhans cells
2
Q
CD2
A
Pan-T cell/NK cell
3
Q
CD3
A
(surface)
Pan T-Cell
4
Q
CD4
A
Helper/inducer T cells
5
Q
CD5 (2)
A
- Pan-T cell
- Subset of B cells
6
Q
CD7
A
Pan-T cell/NK cell
7
Q
CD8
A
Cytotoxic/suppressor T cell
8
Q
CD9 (3)
A
- B cells
- Platelets
- Megakaryotcytes
9
Q
CD10 (3)
A
- Immature and germinal center B cells
- Neutrophils
- Follicular helper T cells
10
Q
CD11b (2)
A
- Maturing and mature myelomonocytic cells
- NK cells
11
Q
CD11c (3)
A
- Maturing and mature myelomonocytic cells
- Myeloid dendritic cells
- Some B cells
12
Q
CD13
A
Pan-myeloid cells
13
Q
CD14 (2)
A
- Maturing and mature monocytes
- Mature neutrophils
14
Q
CD15
A
Maturing and mature myelomonocytic cells
15
Q
CD16 (2)
A
- Late-stage neutrophil
- NK cells
16
Q
CD19
A
Pan-B cell (including immature forms and plasma cells)
17
Q
CD20
A
Maturing and mature B cells
- Will be falsely negative if pt tx with rituxumab (or other anti-CD20)
18
Q
CD22
A
Maturing and mature B cells
19
Q
CD21
A
Follicular dendritic cell meshwork within germinal center
20
Q
CD23 (*2)
A
- Activated B cells
- Follicular dendritic cell meshwork
21
Q
CD25
A
Activated T and B cells
22
Q
CD30
A
Activated T and B cells
23
Q
CD33
A
Pan-myeloid cell
24
Q
CD34 (2)
A
- Myeloid and lymphoid blasts
- Stem cells
25
CD38 (5)
- Plasma cells
- Blasts
- Activated B and T cells
- NK cells
- Monocytes
26
CD41 (2)
Platelets and megakaryocytes
27
CD45
Leukocyte common antigen (all hematopoietic cells except later erythroids)
28
CD56 (2)
- NK cells
| - Activated T cells
29
CD57
Subset of cytotoxic and suppressor T cells
30
CD61 (2)
Platelets and megakaryocytes
31
CD64 (3)
- Monocytes
- Immature granulocytes
- Activated neutrophils
32
CD103
Enteric T cells
33
CD117/c-kit (4)
- Myeloid blasts
- Promyelocytes
- Proerythroblasts
- Mast cells
34
CD123 (3)
- Basophils
- Plasmacytoid dendritic cells
- Some blasts
35
CD133
Immature progenitor cells
36
BCL-2 (2)
- Most mature B cells except germinal center cells (anti-apoptotic marker)
- Most T cells
37
HLA-DR (5)
- Myeloid balsts
- All B cells
- Activated T cells
- Monocytes
- Dendritic cells
38
FMC7
Variety of mature B cells (a CD20 epitope)
39
kappa light chain (2)
- Mature B cells
| - Plasma cells
40
lambda light chain (2)
- Mature B cells
| - Plasma cells
41
TdT
Immature B and T cells
42
Zap-70 (2)
- T cells
| - NK cells
