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Pathology > IHCs > Flashcards

IHCs Flashcards

1
Q

CD1a (2)

A
  • Immature T cells (common thymocytes)

- Langerhans cells

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2
Q

CD2

A

Pan-T cell/NK cell

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3
Q

CD3

A

(surface)

Pan T-Cell

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4
Q

CD4

A

Helper/inducer T cells

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5
Q

CD5 (2)

A
  • Pan-T cell

- Subset of B cells

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6
Q

CD7

A

Pan-T cell/NK cell

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7
Q

CD8

A

Cytotoxic/suppressor T cell

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8
Q

CD9 (3)

A
  • B cells
  • Platelets
  • Megakaryotcytes
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9
Q

CD10 (3)

A
  • Immature and germinal center B cells
  • Neutrophils
  • Follicular helper T cells
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10
Q

CD11b (2)

A
  • Maturing and mature myelomonocytic cells

- NK cells

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11
Q

CD11c (3)

A
  • Maturing and mature myelomonocytic cells
  • Myeloid dendritic cells
  • Some B cells
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12
Q

CD13

A

Pan-myeloid cells

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13
Q

CD14 (2)

A
  • Maturing and mature monocytes

- Mature neutrophils

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14
Q

CD15

A

Maturing and mature myelomonocytic cells

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15
Q

CD16 (2)

A
  • Late-stage neutrophil

- NK cells

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16
Q

CD19

A

Pan-B cell (including immature forms and plasma cells)

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17
Q

CD20

A

Maturing and mature B cells

- Will be falsely negative if pt tx with rituxumab (or other anti-CD20)

18
Q

CD22

A

Maturing and mature B cells

19
Q

CD21

A

Follicular dendritic cell meshwork within germinal center

20
Q

CD23 (*2)

A
  • Activated B cells

- Follicular dendritic cell meshwork

21
Q

CD25

A

Activated T and B cells

22
Q

CD30

A

Activated T and B cells

23
Q

CD33

A

Pan-myeloid cell

24
Q

CD34 (2)

A
  • Myeloid and lymphoid blasts

- Stem cells

25
Q

CD38 (5)

A
  • Plasma cells
  • Blasts
  • Activated B and T cells
  • NK cells
  • Monocytes
26
Q

CD41 (2)

A

Platelets and megakaryocytes

27
Q

CD45

A

Leukocyte common antigen (all hematopoietic cells except later erythroids)

28
Q

CD56 (2)

A
  • NK cells

- Activated T cells

29
Q

CD57

A

Subset of cytotoxic and suppressor T cells

30
Q

CD61 (2)

A

Platelets and megakaryocytes

31
Q

CD64 (3)

A
  • Monocytes
  • Immature granulocytes
  • Activated neutrophils
32
Q

CD103

A

Enteric T cells

33
Q

CD117/c-kit (4)

A
  • Myeloid blasts
  • Promyelocytes
  • Proerythroblasts
  • Mast cells
34
Q

CD123 (3)

A
  • Basophils
  • Plasmacytoid dendritic cells
  • Some blasts
35
Q

CD133

A

Immature progenitor cells

36
Q

BCL-2 (2)

A
  • Most mature B cells except germinal center cells (anti-apoptotic marker)
  • Most T cells
37
Q

HLA-DR (5)

A
  • Myeloid balsts
  • All B cells
  • Activated T cells
  • Monocytes
  • Dendritic cells
38
Q

FMC7

A

Variety of mature B cells (a CD20 epitope)

39
Q

kappa light chain (2)

A
  • Mature B cells

- Plasma cells

40
Q

lambda light chain (2)

A
  • Mature B cells

- Plasma cells

41
Q

TdT

A

Immature B and T cells

42
Q

Zap-70 (2)

A
  • T cells

- NK cells

Pathology (4 decks)

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