ih Flashcards
Reagent used to detect presence of
ABO subgroups
a. anti-A
b. anti-B
c.Anti-A,B
d. all of the choices
c
Produces a mixed-field reaction
with polyclonal anti-A and
polyclonal anti-A,B
a. A1
b.A2
c.A3
d. A
c
Hemolytic transfusion reaction
occurs when a weak subgroup A
receives blood from type O blood.
a.True
b.False
b
The type of hemolytic transfusion
reaction caused by incompatible
transfusion from ABO blood group
a.Extravascular hemolysis
b.Intravascular hemolysis
b
A person with a genotype AO is
phenotyped as
a.A
b.O
c. AO
a
“O” expresses no antigen hence, it is
a. Amorph
b. recessive
c.both
a
Anti-A and Anti-B are predominantly
a.IgG
b.IgM
c. IgG and IgM
b
Detected in the ABO forward typing
a.Antigen
b.antibody
a
Reagents used in reverse typing
a. anti-A, anti-B
b. A1 and B cells
c. either
b
Which among the following can be a
problem with forward grouping?
a. cold autoantibodies
b. newborn
c.Bone marrow transplant
c
Causes delayed hemolytic
transfusion reaction
a. kell
b.Kidd
c. duffy
d. Rh
b
Phenotype of Lewis secretor
a. Le(a+b)
b. Le (a-b+)
c. Le(a-b-)
b
Requires a blood warmer for
transfusion
a. anti-l
b. anti-i
c.anti-P
d. anti-lu
c
Implicated in HTR and HDFN
a. anti-Lu
b. anti-Lub
c. both
b
Enzyme treated cells may be used
a.FyFy
b.MNSs
c.JkaJkb
d.all of the choices
c
Rh antibodies are
a. cold antibodies
b.Warm antibodies
c. both
b
Rhogam (RhIG) is administered
a. within 72 hrs. pre-delivery
b. within 72 hrs. post-delivery
b
An individual who lacks K antigens
but have Kx antigen
a. Knull
b.Ko
c.Both
c
Mcleod phenotype
a.Lacks Kx
b. marked expression of Kell
antigens
c.both
a
Resistant to malarial infection by
Plasmodium vivax
a.Duffy negative
b. Duffy positive
c. neither
a
What antibodies are formed by a
Bombay individual?
a. anti-A and anti-B
b. anti-H
c. anti-A,3
d.Anti-A,B and H
d
If a parent has the Rh genotype R1R1
and receives a unit of R packed red
blood cells from an R1r individual,
what Rh antibody might the patient
develop?
1. Anti-E;
2. Anti-e;
3. Anti-C;
4. Anti-c
4
What possible genotype for a patient
who develops anti-E antibody?
1. R2r;
2. R1R1;
3. r2r2;
4. Rr;
4
HDFN occurs due to which of the
following blood incompatibilities
between mother and fetus?
a. mother Rh+, fetus Rh-
b. mother Rh-, fetus Rh+
C. Both
b
A father who is Rh+ and mother who
is Rh- will most likely result to
developing HDFN to the first and
succeeding pregnancies
a.True
b.False
b
HDFN results due to the reaction
between the fetal antibodies to the
maternal red cells.
a.True
B.False
b
A type “O” fetus would most likely
develop a non-severe type of HDFN
if the mother is “A”, “B”, or “AB”.
a.True
b.False
b
Antigen system NOT initially present
on the red blood cell surface is
a. Duffy
b.Lewis
b
I antigen is found in
a.all newborn:no adults
b.No newborns; all adults
c.no human beings
d.all persons to some degree
b
Rh antibodies react best at what
temperature?
a. 22C
b 18C
c. 150
d. 37C
d
Rh antibodies are primarily of which
immunoglobulin class?
A.IgA
B.IgM
C. IgG
D.IgD
c
Non-specific reaction
a.acquired immunity
b.Innate immunity
b
Immune response to transfused
incompatible HLA antigens causes
fever and chills
a. Febrile, non-hemolytic
transfusion reaction
b.Febrile,hemolytic transfusion
reaction
c.non-febrile, non hemolytic
transfusion reaction
d. non-febrile, hemolytic
transfusion reaction
a
Single immunoglobulin unit
a.IgG
b.IgM
c.both
a
Membranes of platelet have protein
antigens
a.True
b.false
a
Clinically important antibodies best
react at
a.20-24C
B.37ºC
c.depending on the type of
antibody detected
b
Antibody excess
a.Post-zone
b.Pro-zone
b
A cloudy solution appears in
hemagglutination reported as
a.1+
b. 2+
c.3+
d.4+
e.all of the choices
a
Actual genetic make-up
a.Genotype
b.phenotype
c.genetic focus
d.gene
a
Having two or more possible alleles
at a locus
a.antiethical
b.dominant
c.Polymorphic
d.recessive
c
Inheritance of identical alleles
a.Homozygous
b.heteroxygous
c.dominant
d.recessive
a
Agglutination reactions are
generally stronger for homozygous
cells and slightly weaker for
heterozygous cells
a.Cis
B.Dosage
c.Trans
b
Full expressions of ABO antigens
a.6months-1year
b.2-4years
b
Sugar attached to B antigens of the
ABO
a.N-acetylgalactosamine
b.D-galactose
c.L-fructose
b
Agglutinates of the A subgroups of
the ABO
a.anti A
b.anti B
c.Anti-A,B
c
An amorph allele
a.A
b.B
c.AB
d.O
d
Clinical specimen for ABO forward
typing
A.RBC suspension
B.serum
C. either
a
Bombay phenotype
a.OH
b.Oh
Which of the following is not a
secretor?
a.Sese
b.sese
c.SeSe
d.none of the choices
b
Weak D individuals are
a.Rh negative
b.Rh positive
b
A partial D individual
a. Rh positive
b. Rh negative
c. able to produce anti-D
d. A and C
d
Knull
a.lacks Kx antigen
b. Increase amount of Kx
antigen
b
Clinically significant antibody
a.anti-Le
b.anti-I
c.anti-P
D.anti-Lub
e.all of the choices
d
Enzyme treatment is possible
a.FyFy
b.MNSs
c.JkaJkb
d.all of the choices
c
Determines capability of donor RBCs
with recipient’s blood
a.antibody screen
b.antibody identification
c.Crossmatch
c
Enhances the formation of antigen-
antibody complexes
A.antisera
b.antiglobulin reagents
C.Potentiators
c
Check cells ensure negative
antiglobulin test hence, a valid result
is
a.Agglutination
b.no agglutionation
a
Detects ABO antibodies
a.antibody screening test
b.antibody panel cells
c.forward typing
d.Reverse type
d
Detects in vivo agglutination
a.DAT
b. IAT
a
Detects in vitro agglutination
a.DAT
b.IAT
b
