Ie Flashcards
What is the Viridans group streptococci’s resistance to?
Relative resistant to penicillin
What is the treatment for native infective endocarditis caused by Staph aureus?
IV cloxacillin (if methicillin sensitive)
What is the treatment for prosthetic infective endocarditis caused by Staph aureus?
IV vancomycin if MRSA, both 4 - 6 weeks
What is the treatment for Enterococcus in native infective endocarditis?
IV ampicillin + gentamicin
What is the treatment for Enterococcus in prosthetic infective endocarditis?
IV vancomycin (MRSA) or IV cloxacillin (MSSA)
What is the treatment for HACEK group in native infective endocarditis?
IV ceftriaxone
What is the proper monitoring in the ward for infective endocarditis?
Fever chart, signs of heart failure, embolic phenomenon, laboratory tests
What signs may indicate a suppurative complication in infective endocarditis?
Prolonged non-resolved fever
What are the symptoms of heart failure to monitor in infective endocarditis?
Lung crepitation, leg oedema
What laboratory tests should be performed in infective endocarditis?
Inflammatory markers, FBC, renal profile, LFT
What is the target pre-dose blood gentamicin level?
Should be < 1 mg/L
How often should blood gentamicin levels and renal profiles be monitored?
Weekly
What is the duration for gentamicin treatment in infective endocarditis?
2 - 4 weeks
What are the major criteria for diagnosing infective endocarditis?
Positive blood culture of typical organism, evidence of endocardial involvement in echo
What are the common organisms implicated in infective endocarditis?
Staphylococcus aureus, Viridans group streptococci, Staphylococcus epidermidis, Enterococci, HACEK group
What are the risk factors for infective endocarditis?
IVDU, prosthetic heart valve, dental procedure, poor dental hygiene
What is the procedure for taking blood culture for an infective endocarditis patient?
Use aseptic technique, necessary items include blood C+S bottles, needles, syringes, etc.
