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CPTC 2018 > IDT/ HLA > Flashcards

IDT/ HLA Flashcards

1
Q

Hepatitis B

Serology Window

A

60 days

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2
Q

Hepatitis B

NAT Window

A

20 Days

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3
Q

Hepatitis C

Serology Window

A

70 Days

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4
Q

Hepatitis C

NAT Window

A

7 Days

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5
Q

HIV

Serology Window

A

23 days

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6
Q

HIV

NAT Window

A

7 Days

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7
Q 
Hep B 
Surface Antibody (sAb) +
A

Vaccinated

transfused from a immunized donor

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8
Q

Heb B
Surface Antigen (sAg) +
Core (cAb) +

A

Active Infection

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9
Q

Hep B
Surface Antibody (sAb) +
Core (cAb) +

A

Resolved

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10
Q

HBsAg

A

Hep B Surface Antigen

+ = infection

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11
Q

HBcAb

A

Hep B Core Antibody
Active or resolved disease
may be only marker of early infection
Not influenced by exposure to vaccine

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12
Q

Mandatory Infectious Disease Testing

A

a. HIV antibody (anti-HIV) donor screening test or HIV antigen/antibody (Ag/Ab) combination test
b. Hepatitis B surface antigen (HBsAg)
c. Hepatitis B core antibody (anti-HBc)
d. Hepatitis C antibody donor screening test (anti-HCV)
e. Hepatitis C ribonucleic acid (RNA) by donor screening or diagnostic nucleic acid test (NAT)
f. Cytomegalovirus (CMV) antibody (anti-CMV)
g. Epstein-Barr Virus (EBV) antibody (anti-EBV)
h. Syphilis donor screening
i. Toxoplasma Immunoglobulin G (IgG) antibody test

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13
Q

When would Transplant center is requesting pre-surgical nodes for tissue typing

A

your donor received a lot of blood products and steroid treatments

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14
Q

If 6 antigen mismatches are identified on your donor it means?

A

less likely chance of rejection; less likely chance of finding a recipient; Allocation will occur to national patients last

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15
Q

Total blood volume calc

A

donor’s weight in Kg divided by 0.015.

Round to the nearest tenth.

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16
Q

Total Plasma Volume calc

A

donor’s weight in Kg divided by 0.025.

Round to the nearest tenth.

17
Q

Hemodilution- Total Infused

A

calculated amount of all infusion given to the patient by adding all blood and colloids given within
48 hours prior to blood draw
Round to the nearest tenth

18
Q

Hemodilution- What period of time do you need to account for with blood and colloids

A

48 hours prior to blood draw

19
Q

Hemodilution- Plasma Infusions

A

calculated amount of colloids given within 48 hours prior to blood draw
and adding all crystalloids given 1 hour prior to blood draw

20
Q

Hemodilution- What period of time do you need to account for with Crystalloid

A

1 hour prior to blood draw

21
Q

Blood Products

A

PRBC
Whole Blood
Reconstituted Blood

22
Q

Colloids

A

Fresh Frozen Plasma (FFP), Platelets, Cryoprecipitates
Plasmanate, Plasma Protein Fraction,
Albumin, Dextran, Hespan, Hetastarch, Plasbumin, Volven

23
Q

Crystalloids

A

Medications, Normal Saline (NS), Lactated Ringers (LR), Dextrose Solutions (D5W) and/or Hyperalimentation Fluids (TPN)

24
Q

If Donor is <28 days old what also must be done?

A

sample MUST be obtained from the birth mother

25
Q

HBsAb+

A

Vaccinated

26
Q

What Heb B sero would be + if vaccinated

A

HBsAb ONLY

27
Q

HBsAg

A

current hepatitis B infection.

28
Q

HBsAb+

HBcAb+

A

RESOLVED INFECTION
infected or exposed to hepatitis B virus in the past, cleared the virus, and are now immune against another infection with hepatitis B.

29
Q

HBcAb+

A

once were infected with hepatitis B

30
Q

Candidates with high PRA indicates what?

A

high likely-hood of a positive crossmatch

31
Q

how many antigens are used to determine tissue typing / crossmatches

A

6

32
Q

what does a positive crossmatch indicate

A

organ is unacceptable for candidate

CPTC 2018 (8 decks)

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