IDIT 3 Flashcards
P. aeruginosa
Exotoxin A, Exoenzyme S (ADP-ribostransferase), type 3 secretions, and a capsule
Loves water and has 2 pigments
Vibrio general
Alkaline media and curved
V. Cholerae
Rice water stool
ADP ribosylation and adenylate cyclase stays active, can lead to shock and acidosis
V. parahaemolyticus
Needs salt for growth
Undercooked seafood
Explosive watery diarrhea mostly in Japan
V. vulnificus
Contaminated seawater and from raw oysters
High death if liver disease and no Abx
C. jejuni
Highly motile, many hosts
Microaerophilic
Bloody, mucopurulent diarrhea, with Abd Cramps
H. pylori
Toxin VacA, CagA with type 4 secretions
IL-8 release
E. Coli
Travelers diarrhea
K antigen
Most common for UTI/Sepsis/meningitis
S. dysenteriae
Cannot ferment mannitol
Actin rockets
Bloody diarrhea with pus and mucus
Type 3 secretions
S. Flexneri
Actin rockets
Bloody diarrhea with pus and mucus
Type 3 secretions
Shigellosis
S. boydii
Same as the other shigellas
S. sonnei
Does not produce gas
Bloody diarrhea with pus and mucus
Type 3 secretions
Shigellosis
Salmonella Typhi
Does not produce hydrogen sulfide Vi antigen, capsule, lps and can reach lamina propria SPI1 for invasion, SPI2 in macrophages Type 3 secretion Gallbladder resevoir
Salmonella enteritidis
Same as typhi but produces gas and makes gastroenteritis and do not use Abx
Gallbladder resevoir
Salmonella chole and dublin
Same as typhi except it does produce gas and septicemia
Gallbladder resevoir
Klebsiella
Encapsulated, opportunistic, and lactose fermenting
Lower respiratory, blood, GU
Proteus
Deaminase, Urease, and raises pH of urine
Weil felix reaction and has O antigen
Mostly GI and is hypermobile
Yersinia
Enterocolitica (appendicitis like)
Cold weather dominant and from milk
Enterobacter
Weak opportunistic
Lower respiratory, blood, burns, UTI
Serratio marcescens
Slow fermenting
Opportunistic after Abx
Resp, UTI, OSTEOMYELITIS, and wounds
Haemophilis influenza
Pediatric meningitis and sepsis
Type B(polyribosyl phosphate), IgA protease
Treat with cefotaxime and rifampin prophylaxis
Choco agar with V(NAD) and X (heme)
Bordetella pertussis
Whooping cough
Adenylate cyclase toxin and induces NOS
Grow in Bordet-Gengou media
Treat with Erythromycin
Legionella pneumophilia
Atipical pneumonia
Makes endosome look like rER
Grow in charcoal yeast media with Fe and cystein
Erythromycin and fluoroquinolones
Brucella abortus/suis/melitensis
cattle/swine/goats Undulating fever Granulomas with caseation Blood broth Use rifampin
Francisella tularansis
Ulcerative glandular disease
Has capsule
Use tetracyclin and streptomycin
Dx with Abs
Yersinia pestis
Vaccine for bubonic, not pneumonic Coagulase produced in GI by type 3 secretions Bipolar safety pin stain Bubonic in lymph treat with tetra and streptomycin
M. pneumoniae
Atipical pneumonia
Looks like mulberries
Has cytoadhesions, less severe than bordetalla
ROS, superantigens bind to MHC2 and bV-TNF
Non productive cough
Use gold agglutin test, pcr, immunoblot, hybrid
M. hominis
PID
Agar with arginine
Ureaplasma urealyticum
Non gonococcal urithritis
Urease positive
M. penetrans
HIV patients that are intracellular
