IDIT Flashcards

1
Q

What infects T cells with a T cell defect

A

Viruses and intracellular shit

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What infects B cells with a B cell difficiency

A

Bacteria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

X linked lymphopenic hypogammaglobulinemia

A

y-chain of IL-2 receptor

Affects everything

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Rag 1 Rag 2

A

autosomal T cell and B cell SCID

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

a- chain of IL2

A

Defective T cell autosomal SCID

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

ADA difficiency

A

Multiple cells affected, autosomal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Wiskott aldrich syndrome

A

Gets Worse with age, B and T cell Actin problem

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

DiGeorge syndrome

A

Athymic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Ataxia telangiectasio

A

T cell defect Chromosome 14 problem in a/delta locus and IgH chains

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Tap

A

Lack of MHC 1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Bare lymphocyte syndrome

A

Lack of MHC 2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

X-linked hypogammaglobulinemia

A

B cell defect with no light chain, All Abs low

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

X-linked hyper igM

A

CD40L on T-cell defect, unable to class switch

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Selective dificiencies

A

Mostly with IgA, is a defect outside Ig genes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Chronic granulomatous disease

A

Defective oxidative burst in phagocites because a lack of NADPH oxidase activity, confirm with NBT dye, have excessive inflamation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly