Idiopathic Pulmonary Fibrosis (IPF) Flashcards
1
Q
what is it
A
imbalance in fibrotic repair system of lungs = lay down unrequired scar tissue
chronic inflammatory infiltrate (neutrophils) causes fibrosis in alveolar walls and macrophages
2
Q
what does it cause increased risk of
A
infection
3
Q
prevalence
A
more common in males
4
Q
causes
A
idiopathic
5
Q
secondary causes
A
rheumatoid, SLE, system scleorisis, asbestosis, drugs
6
Q
symptoms
A
progressive exertional dyspnoea
dry cough
7
Q
signs
A
clubbing
bibasal crackles on auscultation
dry cough
8
Q
diagnosis
A
CXR - bilateral infiltrates, fine inspiratory crackles
HRCT - bilateral lower zone fibrosis/shadowing - ground glass
restrictive PFT and low TLCO
9
Q
treatment
A
oral steroids immunosuppressants (azathioprine) O2 if hypoxic pulmonary rehab lung transplant in young patients
10
Q
complications
A
respiratory failure
most patients dead in 5 years
