IDA Flashcards
First line therapy
Fe sulphate
Iron therapy for IDA pregnant
60-120mg +
400ug Folic acid
Poor pregnancy outcome hgb levels?
Lt 6g/dl
Fe requirement How many times higher for vegetarians
1.8
Fe Dissolve rapidly in?
Stomach
Not recommended form of fe tablet
Enteric coated
Daily supplementation should be how many doses
2/3
When should fe be taken
1 hr preprandial
Fe better taken with?
Vitamin c
Fe should not be taken w?
Milk caffeine
Tea
Wine legumes
If the px has gastrointestinal upset what will u do w fe intake?
Half dose initially
If px has constipation, what med is allowed to take?
Docusate sodium
For follow up, the px hgb increases what should be done next?
Lower dose to 30mg
Adequate fe replacement in pregnant px when?
Ferritin 50u/L
Moderate to sever anemia supplementation
Parenteral
Give 5 Indications of parenteral fe
Malabsorption Intolerance to oral fe Hgb 7-10.5g/dL Need for rapid effect Non compliance
Advantage of parenteral fe
Less risk transmission of infection
Long shelf life
Not aw blood transfusion reactions
More stable than dextrans and gluconate
Iron sucrose
Fe form Less binding to transport proteins,low stability
Sodium fe gluconate
20 wks gestation IDA, parenteral herapy recommended?
No, after 21wks
Formula to compute ID
Target-actual x wt x 0.24 + 500mg
Target is 12, weight is 50kg what is ID when hgb is 10
ID 524?
Dosing schedule? 2 ampuoles/ 100mL PNSS
Infused for 1 hr
_______ is prudent before giving the therapeutic dose
Test dose
Test dose?
0.5ml 10 mg iron sucrose
Hgb level for bloos transfusion
< 7 g
EPO therapy dose w iron sucrose
10 000 units
Hgb <9g/dl
200mg iron sucrose 2x/ wk
If blood falls below 6g/dL
Transfuse blood
Adverse effect of blood transfusion
Hemolysis
GVHD
Fever, chills
Major cause of anemia in perpartal
Acute hemorrhage
Ways to maintain intravascular homeostasis
- Use of dextrans w preacution in px with hemostatic deficit
- Maintain normothermia perioperative
- Fluid shifting( crytalloids for urine; colloid for acute blood loss)
- Hypovolemia tx w crystalloid or colloid
- Blood transfusion only when less than 7g/dL
Prevention strategies?
Food based
Iron supplement
Food based approach?
Dietary
Food fortified
Recommended for 1st trimester?
27mg/day
Dietary for lactating
Amennorheic 27
Richest sources of iron
Liver and glands
Dietary iron exists as
Heme
Nonheme
Alkaline pH is favored for this iron
Heme
Enhancers of iron
Heme(meat…)
Vitc
Fermented food
Inhibitor of iron
Phytates
High inositol
Phenolic cmpds
Calcium
Alterations in meal pattern
Dont drink tea, milk, cheese(dairy)
Include fruit juice
Adding nutrient during processing of food
Food fortification
Most common strategy to prevent IDA
Iron supplementation
For prevention what dose?
60mg/day for 3 months
What if patient is to preven ida and shes in 26 weeks gestation what dose?
120 mg
Pregnant woman resides in an endemic area what should u give?
Antihelminthic
+iron
Px is 6 mos post partum
She has hgb 129
Ferritin 12
Id without anemia
Definitive dx of ida
Iron status
Universal routine low dose fe at first prenatal visit
30mg
Severe anemia
Hgb 6.9-7.9
Mild anemia
9.5-10.5