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ID memorize from school Flashcards

1
Q

Gram positive cluster (2)

A
  1. Staphylococcus Aureus
  2. Staphylococcus Epidermidis
  3. “The ideal staff works in clusters”
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2
Q

Gram positive pair and chains (5)

A

(Streptococcus Enterococcus)

  1. Streptococcus Pneumoniae
  2. Streptococcus Pyogenes (GAS)
  3. Streptococcus Agalactiae (GBS)
  4. Enterococcus Faecalis
  5. Enterococcus Faecium
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3
Q

Gram positive Bacilli

A

Listeria Monocytogenes

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4
Q

Gram Negative Cocci pairs and chains (2)

A
  1. Neisseria sp.

2. Moraxella Catarrhalis

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5
Q

Gram Negative Bacilli Enterobacteriaceae (7)

A
  1. Escherichia Coli (extended spectrum B-lactam)
  2. Klebsiella sp.(ESBL)
  3. Serratia sp.
  4. Proteus sp.
  5. Citrobacter sp.
  6. Enterobacter sp.
  7. Morganella sp.
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6
Q

Gram negative Bacilli Pseudomonads

A
  1. Pseudomonas Aeruginosa

2. Acinetobacter sp.

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7
Q

Gram negative Coccobacilli

A

Haemophilus sp.

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8
Q

Atypicals (3)

A

MCL

  1. Mycoplasma pneumoniae
  2. Chlamydia sp.
  3. Legionella Pneumophila
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9
Q

Anaerobes (2)

A
  1. Clostridium sp.

2. Bacteroides sp.

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10
Q

Reliable Anti-MRSA antibiotic (6)

A

“LINE up the TIGEr TARO cards in the BAC of D APT with the TELa in the VAN”

  1. Vancomycin/telavancin
  2. Linezolid
  3. Daptomycin
  4. Tigecycline
  5. Ceftaroline
  6. TMP/SMX
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11
Q

Less reliable Anti-MRSA antibiotic (2)

A
  1. Doxycycline

2. Clindamycin

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12
Q

Infrequently used MRSA (4)

A
  1. Rifampin
  2. Quinupristin / Dalfopristin
  3. Chloramphenicol
  4. Nitrofurantoin
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13
Q

Antibiotics Active against pseudomonas aeruginosa (14)

A
  1. Piperacillin/tazo
  2. Ticarcillin/clav
  3. Ceftazidime
  4. Cefepime
  5. Aztreonam
  6. Imipenem/cil
  7. Meropenem
  8. Doripenem
  9. Gentamicin
  10. Trobramycin
  11. Amikacin
  12. Ciprofloxacin
  13. Levofloxacin
  14. Colistin
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14
Q

Gram-positive (only – ish) also name exeptions (5)

A
  1. Vancomycin Exception PO – c. diff
  2. Daptomycin
  3. Linezolid Atypical coverage too
  4. Clindamycin Anaerobic coverage too
  5. Quinupristin/Dalfopristin Very little Gram-neg
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15
Q

Anaerobe Coverage (4 classes with multiple agents, 3 agents)

A
  1. PCN - amp/sulb, amox/clav, pip/tazo, ticar/clav
  2. Ceph – cefoxitin, Cefotetan
  3. Carbs – ALL
  4. FQ – levo, moxi
  5. Clindamycin “CMT”
  6. Metronidazole
  7. Tigecycline
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16
Q

Clostridium Difficile Coverage (2)

A
  1. Oral Vancomycin

2. Oral Metronidazole

17
Q

Atypical Coverage (3 classes with multiple agents, 1 agent)

A
  1. Macrolides – ALL
  2. Tetracyclines – ALL
  3. FQ – levo, moxi
  4. Linezolid
18
Q

Gram-negative only (1 class, 3 agents)

A
  1. AG - ALL
  2. Ceftazidime
  3. Aztreonam
  4. Colistin
19
Q

Enterococcus – UTI (3 agents)

A
  1. Doxycycline
  2. Ciprofloxacin
  3. Nitrofurantoin
20
Q

Enterococcus (systemic infx) Sensitive

A
  1. Amp/amox/pen ± BLI, pip/taz, ticar/clav

2. Carbapenems – ALL

21
Q

Enterococcus (systemic infx) 2nd line treatment

A

Vancomycin

22
Q

Enterococcus (systemic infx) resistant

A

“DLT sandwich”

  1. Daptomycin
  2. Linezolid
  3. Tigecycline
23
Q

Post antibiotic effect (6)

A

1 . Peak/MIC = Maximize concentrations “DAMNT I didn’t know they’d last so long”

  1. Daptomycin
  2. Aminoglycosides
  3. Metronidazole
  4. Nitrofurantoin
  5. TMP/SMX?
24
Q

Time dependent killing (5)

A
  1. T>MIC = Maximize duration
  2. Penicillins
  3. Cephalosporins
  4. Carbapenems
  5. Monobactams
25
Q

Both time and concentration dependent killing (AUC/MIC) (4 classes, 1 drug)

A
  1. AUC/MIC = maximize amount of drug
  2. Fluoroquinolone
  3. Macrolides
  4. Glycopeptides
  5. Tetracycline
  6. Linezolid
26
Q

% Goal T>MIC (4)

A
  1. Percent time above MIC during interval
  2. Cephalosporins 60%
  3. Penicillins 50%
  4. Carbapenems 40%
27
Q

Aminoglycoside PD Goal? What is the equation?

A
  1. For G negative is 16x the MIC

2. Concentration (16xMIC)= Dose/Volume

28
Q

Aminoglycoside Gram Dosing Differences What would the dosing be in gram (+)?

A
  1. G neg = 5-7mg/kg

2. G pos = 1mg/kg

29
Q

70kg receiving 350mg of gent what type of bacteria would be treating?

A

305mg/70kg = 5 mg (Gram negative)

30
Q

Fluoroquinolone PD goal for gram (+) and (-)?

A

G pos = AUCfree/MIC>25

G neg = AUC/MIC>125

31
Q

High Tissue Distribution (6)

A
  1. Not good for blood infection
  2. “RT F.M.”
  3. Rifampin
  4. Tetracycline
  5. Fluoroquinolone
  6. Macrolide
32
Q

Low Tissue Distribution (5)

A
  1. “A.C. at the D.Q/d cold at dairy queen”
  2. Amnioglycoside
  3. Colistin
  4. Daptomycin (useless for pneumonia due to being bound to surfactant)
  5. Q/D
33
Q

MOA of Cell Wall inhibitor (1 class, 4 drugs, 1 reminder)

A
  1. “BVD Co. underwear”
  2. Beta Lactams
  3. Vancomycin/Telvancin
  4. Daptomycin
  5. Colistin
34
Q

MOA of DNA inhbition (1 class, 5 drugs, 1 reminder)

A
  1. “MR. BNF”
  2. Metronidazole
  3. Rifampin
  4. TMP/SMX
  5. Nitrofurantoin
  6. Fluoroquinolone
35
Q

MOA of Protein Inhibition (3 class, 3 drugs)

A
  1. Amnioglycosides
  2. Macrolide
  3. Tetracycline
  4. Clindamycin
  5. Linezolid
  6. Quinupristin/Dalfopristin

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