ID I - ABX Coverages Flashcards

1
Q

Natural penicillins - coverage

A

-Strep.
-Enterococci
-NOT STAPH!
-Gram positive anaerobic mouth flora (peptostreptococci, actinomyces)

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2
Q

Natural penicillins - drugs

A

-Penicillin V Potassium
-Penicillin G Aqueous
-Penicillin G benzathine (will cover VRE E. faecalis)

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3
Q

Aminopenicillins - coverage

A

-Strep.
-Enterococci
-NOT STAPH!
-Gram positive anaerobic mouth flora (peptostreptococci, actinomyces)
-HNPE

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4
Q

Aminopenicillins + beta lactamase inhibitors - coverage

A

-Strep.
-Enterococci
-Staph. coverage
-Gram positive anaerobic mouth flora (peptostreptococci, actinomyces)
-HNPEK
-B. fragilis (gram negative anaerobe)

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5
Q

Aminopenicillins - drugs

A

-Amoxicillin
-Ampicillin

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6
Q

Extended-Spectrum Penicillin + beta lactamase inhibitor - drug AND coverage

A

Drug: piperacillin-tazobactam
Coverage (broad):
-Strep.
-Enterococci
-Staph. coverage
-Gram positive anaerobic mouth flora (peptostreptococci, actinomyces)
-HNPEK
-B. fragilis (gram negative anaerobe)
-CAPES
-P. aeruginosa

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7
Q

Antistaphylococcal penicillins - coverage

A

-Staph.
-Strep.

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8
Q

Antistaphylococcal penicillins - drugs

A

-Dicloxacillin
-Nafcillin
-Oxacillin

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9
Q

1st Gen Cephalosporins - coverage

A

-Staph.
-Strep.
-Some PEK coverage; increases as generations increase

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10
Q

1st Gen Cephalosporins - drugs

A

-Cefazolin
-Cephalexin
-Cefadroxil

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11
Q

2nd Generation Cephalosporins - coverage

A

-Staph.
-Strep.
-HNPEK
*-B. fragilis

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12
Q

2nd Generation Cephalosporins - drugs

A

-Cefuroxime
-Cefaclor
-Cefprozil
*-Cefotetan
*-Cefoxitin

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13
Q

3rd Generations Cephalosporins Group 1 - coverage

A

-Staph.
-Strep.
-HNPEK
-Gram positive anaerobic mouth flora (peptostreptococci, actinomyces)

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14
Q

3rd Generation Cephalosporins Group 1 - drugs

A

-Ceftriaxone
-Cefotaxime
-Cefdinir
-Cefditoren
-Cefixime
-Cefpodoxime
-Ceftibuten

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15
Q

3rd Generation Cephalosporins Group 2 - coverage

A

-NO GRAM POSITIVE ACTIVITY
-Pseudomonas

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16
Q

3rd Generation Cephalosporins Group 2 + beta lactamase inhibitors - coverage

A

-MDR Pseudomonas
-MDR gram negative rods, including ESBL producing

17
Q

3rd Generation Cephalosporins Group 2 - drugs

A

-Ceftazidime
-Ceftolozane

18
Q

4th Gen Cephalosporins - coverage AND drug

A

Drug: cefepime
-Staph.
-Strep.
-Gram positive anaerobic mouth flora (peptostreptococci, actinomyces)
-HNPEK
-CAPES
-Pseudomonas

19
Q

5th Gen Cephalosporin- coverage AND drug

A

Drug: Ceftaroline
-BROAD GRAM POSITIVE (includes MRSA)
-HNPEK

20
Q

Carbapenems - coverage, and the exception

A

Everything EXCEPT:
-Atypicals
-MRSA
-C. diff
-Stenotrophomonas
-VRE
-Enterococcus faecium

EXCEPTION: ertapenem additionally DOES NOT COVER:
-Pseudomonas
-Acinetobacter
-Enterococcus

21
Q

Aztreonam - coverage

A

-Gram negatives, including pseudomonas
-NO GRAM POSITIVE or ANAEROBIC

22
Q

Aminoglycosides - coverage

A

-Gram negatives, including pseudomonas and ESBL
-Gentamicin and streptomycin used in synergy for some gram-positive infections
-Streptomycin and amikacin are second-line for some Mycobacterial infections

23
Q

Respiratory fluoroquinolones - drugs

A

-Gemifloxacin
-Levofloxacin
-Moxifloxacin

24
Q

Fluoroquinolones that cover Pseudomonas - drugs

A

-Ciprofloxacin
-Levofloxacin

25
Q

Fluoroquinolone that CANNOT be used or UTI

A

Moxifloxacin

26
Q

Macrolides - coverage

A

Atypicals

27
Q

Tetracyclines - coverage

A

-Gram positives
-VRE ONLY in cystitis
-Gram negatives
-Atypicals
-Spirochetes
-Rickettsiae
-T. pallidum
-Bacillus anthracis

28
Q

SMX/TMP - coverage

A

-Staph. (including MRSA)
-Many gram negatives, notably Shigella, Salmonella, and Stenotrophomonas
-NOT PSEUDOMONAS
-Opportunistic pathogens: Nocardia, pneumocystis, toxoplasmosis

29
Q

Vancomycin and Lipoglycopeptides - coverage

A

-Gram positives only, including MRSA
-NOT VRE
-Vancomycin PO covers C. diff

30
Q

Daptomycin - coverage

A

-Gram positives, including MRSA and both VRE

31
Q

OxaZOLIDinones - coverage

A

-Gram positives, including MRSA (eh) and both VRE

32
Q

Tigecycline - coverage

A

Everything EXCEPT 3 P’s:
-Pseudomonas
-Proteus
-Providencia

33
Q

Polymyxins - coverage

A

-Broad-spectrum gram negatives EXCEPT Proteus

34
Q

Clindamycin - coverage

A

-Gram positives including MRSA
-NOT ENTEROCOCCI
-Anaerobes

35
Q

Metronidazole and Tinidazole - coverage

A

-Protozoa
-Anaerobes (metronidazole ONLY)

36
Q

Fosfomycin - coverage

A

-E. coli (includes ESBLs)
-E. faecalis (including VRE)

37
Q

Nitrofurantoin - coverage

A

-S. aureus
-Enterococcus (VRE)
-Enterobacter
-E. coli
-Klebsiella