ID

Question 1

What are the side effects of anti TB therapy?

Answer 1

• R: hepatitis, orange urine, enzyme induction
• I: hepatitis, peripheral sensory neuropathy, neutropenia
• P: hepatitis, arthralgia (CI: gout, porphyria)
• E: optic neuritis

Question 2

How do you treat toxoplasmosis?

Answer 2

Pyrimethamine + sulfadiazine + folate

(co trimoxazole for prophylaxis)

Question 3

How do you treat cryptococcal meningitis?

Answer 3

Amphotericin B + flucytosie for 2 weeks then fluconazole for 6 months until CD4 >200

Question 4

What LFT pattern is seen in hepatitis A?

Answer 4

Very high ALT, High AST (AST:ALT <2)

Question 5

What do the different hep B serology results indicate?

Answer 5

• sAg = current infection (including chronic)
• eAG = high infectivity
• HBc IgM = recent infection
• HBc IgG = past infection
• HBs = cleared infectino or vaccinated

Question 6

Which vaccines are live attenuated?

Answer 6

BCG

MMR

oral polio

yellow fever

oral typhoid

Question 7

What are the common causative organisms for meningitis?

Answer 7

0 - 3 months

• Group B Streptococcus (most common cause in neonates)
• E. coli
• Listeria monocytogenes

3 months - 6 years

• Neisseria meningitidis
• Streptococcus pneumoniae
• Haemophilus influenzae

6 years - 60 years

• Neisseria meningitidis
• Streptococcus pneumoniae

> 60 years

• Streptococcus pneumoniae
• Neisseria meningitidis
• Listeria monocytogenes

Immunosuppressed: Listeria monocytogenes

Question 8

What is the definition of SIRS?

Answer 8

two or more of: body temperature above 38C or below 36C, a heart rate > 90 beats per minute, a respiratory rate > 20 breaths per minute, and a peripheral blood white cell count (WCC) of < 4 * 109/l or >12 * 109/l.

Question 9

What is the treatment for non-falciparum malaria?

Answer 9

Chloroquine

Question 10

What should the anti-HbS level be after a hep B vaccine?

Answer 10

• >100 - fine (booster at 5 years)
• 10-100 - do another dose
• <10 - non responder; test for current or past infection, give 3 doses again, then test, if still no response needs HBIG if exposed

Question 11

Which pneumonia is commonly associated with reactivation of herpes/cold sores?

Answer 11

Strep pneumoniae

Question 12

What is Klebsiella pneumonia associated with?

Answer 12

Diabetic and alcoholic patients, cavitating lesions in upper lobe, aspiration, redcurrant jelly haemoptysis.

Question 13

how do you treat legionella?

Answer 13

Clarithromycin

Question 14

How do you diagnose lyme disease?

Answer 14

Blood test for serology

Question 15

What is the treatment for primary genital herpes?

Answer 15

Oral aciclovir (if within 5 days)

Question 16

What is the advice about sports and glandular fever?

Answer 16

No contact sports for 8 weeks after having glandular fever

Question 17

Why give primaquine after chloroquine for vivax or ovale malaria?

Answer 17

to destroy liver hypnozoites and prevent relapse

Question 18

Most common organisms in central line infections

Answer 18

Staph epidermidis

Question 19

Antibiotic for meningococcal meningitis prophylaxis?

Answer 19

Ciprofloxacin

Question 20

Most common cause of diarrhoea in HIV positive patients?

Answer 20

Cryptosporidium

Question 21

What is the treatment for genital warts?

Answer 21

• multiple, non-keratinised warts: topical podophyllum
• solitary, keratinised warts: cryotherapy

Question 22

Treatment for amoebiasis?

Answer 22

Metronidazole

Question 23

How many tetanus vaccines are needed to get lifelong immunity?

Answer 23

5