ID Flashcards
how can neuroinvasive West Nile virus present?
acute flaccid paralysis, which may lead to persistent weakness or death
How does TB meningitis usually present?
classically presents with
- basilar meningitis with cranial neuropathies, mental status changes, SIADH
freshwater exposure in summertime is a key historical clue in what type of meningitis?
acute primary amoebic meningoencephalitis
empiric abx treatment of brain abscesses?
vancomycin + metronidazole + third gen cephalosporin
empiric abx treatment of brain abscesses?
vancomycin + metronidazole + third gen cephalosporin
Mabove what size should a brain abscess usually undergo surgical/ stereotactic drainage?
> 2.5cm
imaging modality of choice to identify location and extent of spinal epidural abscess?
MRI
what virus may cause viral encephalitis presenting with acute flaccid paralysis or Parkinsonism?
West Nile virus
how to diagnose babesiosis?
direct visualisation of the organism on blood smear or PCR
treatment of babesiosis?
atovaquone + azithromycin
1st line abx for uncomplicated pyelonephritis in the US?
ciprofloxacin for 7 days
or levofloxacin for 5 days
ix of histoplasmosis?
histoplasma urinary antigen assay
- >85% sensitivity and specificity in acute and disseminated infection, <50% in chronic infection
ix of histoplasmosis?
histoplasma urinary antigen assay
- >85% sensitivity and specificity in acute and disseminated infection, <50% in chronic infection
tx of choice in histoplasmosis?
itraconazole
- don’t need to treat if mild infection as self resolves
if severe lung disease/ disseminated infection -> liposomal amphotericin B
first line tx of symptomatic coccidiomycosis?
fluconazole