ID Flashcards

1
Q

how can neuroinvasive West Nile virus present?

A

acute flaccid paralysis, which may lead to persistent weakness or death

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2
Q

How does TB meningitis usually present?

A

classically presents with
- basilar meningitis with cranial neuropathies, mental status changes, SIADH

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3
Q

freshwater exposure in summertime is a key historical clue in what type of meningitis?

A

acute primary amoebic meningoencephalitis

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4
Q

empiric abx treatment of brain abscesses?

A

vancomycin + metronidazole + third gen cephalosporin

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5
Q

empiric abx treatment of brain abscesses?

A

vancomycin + metronidazole + third gen cephalosporin

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6
Q

Mabove what size should a brain abscess usually undergo surgical/ stereotactic drainage?

A

> 2.5cm

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7
Q

imaging modality of choice to identify location and extent of spinal epidural abscess?

A

MRI

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8
Q

what virus may cause viral encephalitis presenting with acute flaccid paralysis or Parkinsonism?

A

West Nile virus

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9
Q

how to diagnose babesiosis?

A

direct visualisation of the organism on blood smear or PCR

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10
Q

treatment of babesiosis?

A

atovaquone + azithromycin

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11
Q

1st line abx for uncomplicated pyelonephritis in the US?

A

ciprofloxacin for 7 days
or levofloxacin for 5 days

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12
Q

ix of histoplasmosis?

A

histoplasma urinary antigen assay
- >85% sensitivity and specificity in acute and disseminated infection, <50% in chronic infection

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13
Q

ix of histoplasmosis?

A

histoplasma urinary antigen assay
- >85% sensitivity and specificity in acute and disseminated infection, <50% in chronic infection

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14
Q

tx of choice in histoplasmosis?

A

itraconazole
- don’t need to treat if mild infection as self resolves

if severe lung disease/ disseminated infection -> liposomal amphotericin B

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15
Q

first line tx of symptomatic coccidiomycosis?

A

fluconazole

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16
Q

diagnosis of coccidiomycosis?

A

clinically suspected in endemic area,
can be confirmed by mycologic culture of affected tissues, histopathologic evaluation of tissue, or serology for Coccidiodes antibodies

17
Q

treatment of vibrio vulnificus associated necrotising fasciitis?

A

doxycycline + ceftazidime

18
Q

tx of clostridium perfringens associated necrotising fasciitis?

A

penicillin + clindamycin