ID Flashcards
what is a carrier
person or animal that harbors the infectious agent/disease and can TRANSMIT TO OTHERS but does not demonstrate signs of the disease
- COVID living dormant in your body
what is a contact
exposure to a source of an infection but does not imply infection, just possibilty of infection
what is a host
an organism that harbors a parasitic, mutualistic, or commensalism guest. the host is the house, the parasite is the freeloader
- ex. human
what is a pathway into the host that gives an agent access to tissue that will allow it to multiply or act
portal of entry
what is a pathogen that is transmissible from non-human animals (typically vertebrates) to humans
zoonosis
what is a population of organisms or the specific environment in which an infectious pathogen naturally lives and reproduces; usually a living host of certain species
reservoir
what is the constant presence of an agent or health condition within a given geographical area or population
endemic
what is an increase, often sudden, in number of cases of a disease above what is normally expected in that population and area
epidemic
ex. opiod epidemic in the US
what carries the same definition of epidemic but is often used for a more limited geographical area
outbreak
ex. mississippi
what is any of a group of viruses that are transmitted between hosts by mosquitos, ticks, and other arthropods
Arbovirus (arthropod-borne virus)
what is when a majority of a given group is resistant or immune to a pathogen. For example protection to an unvaccinated or susceptible individuals/group by reducing the likelihood of infection or spread.
Herd immunity
what is transfer of active humoral immunity of ready-made antibodies produced by another host or synthesized. When there is a high risk of infection and insufficient time for the body to develop its own immune response. Short term
passive immunity
- example: Rabies IG, Tetanus IG, Crofab (rattlesnake antivenin)
what is transmission occurring between an infected person and a susceptible person via direct physical contact with blood or body fluids
- person to person
direct contact -infection
what is transmission occurs when there is no direct human to human contact
- vehicle borne: person to contaminated surface/object to person
indirect contact
what type of protozoa group is found in giardia, leishmania. The flagellates
mastigophora
what type of protozoa group is non motile adult stage organisms (ex. plasmodium, cryptosporidium)
sporozoa
what are the three classes of human parasites
protozoa
helminths
ectoparasites
what is the time interval from a person being infected to the onset of symptoms of an infectious disease
incubation period
what is resistance delevoped in response to an antigen characterized by the presence of antibody produced by host
active immunity
what are examples of ectoparasites
ticks, fleas, lice and mites that burrow into the skin and remain there for weeks to months
how is west nile virus transmitted
primary the cullex mosquito; blood transfusion/organ donation, or mother to child
what is the incubation period for west nile
2-6 days but can range from 2-14 days
what is the most prevalent mosquito borne disease in the US
West nile virus
Patient presents to medical following a recent camping trip (JULY) he states he has felt febrile for the last 4 days but mostly noticed a transient maculopapular rash. He said he did not use bug spray and did notice some annoying mosquito bites prior to the rash. What might be the cause
west nile virus
what lab diagnosis is used to confirm WNV
Diagnosis via identifying IgM in serum or CSF
- ELISA is used to detect IgM
note: CBC is NOT A RELIABLE INDICATOR
What is the treatment for someone with WNV
no specfic treatment
- vigorous supporitve measures are the first line management protocol
patients with meningial sx often require pain control for headaches, antiemetic, and rehydration
patients with encephalitis require close monitoring
when would WNV be a MEDEVAC
warranted if there are signs of encephalitis, meningitis, or paralyisis
what are the subtypes of malaria
P. Falciparum
P. vivax
P. ovale
P. Malariae
how is malaria transmitted
via the female anopheles mosquito
what is the incubation period for malaria
7 to 30 days depending of the species of malaria infection
what is the most lethal malaria
P falciparum
patient reports to medical with flu like symptoms such as malaise, chills, headache and a fever that comes and goes for over a week now. He states the only thing he noticed was that he was bit by a mosquito recently but didnt think mosquito bites could make you feel this sick. what might be the diagnosis
malaria
how will malaria be diagnosed
clinical findings consistent with malaria infection
RAPID DIAGNOSTIC TESTING OR LABRATORY CONFIRMATION VIA BLOOD SMEAR
what is the downfall of using rapid malaria testing on board
gives qualitative result but no quantitative information regarding parasite density
both positive and negative results must always be confirmed by micorscopy
what is the treatment for malaria
uncomplicated: Chloroquine phosphate
treatment of P. ovale = Add primaquine
how is dengue fever transmitted
aedes aegypti mosquito
what is dengue fever known as
breakbone fever
what are the three phases of dengue fever
febrile phase
critical phase
convalescent phase
which phase of dengue does most patients clinically improve during and it lasts about 24-48 hours
critical phase
what are the two hallmark symptoms of severe dengue
capillary permeability (leaky capillaries) and disordered/diminished blood clotting
what is a positve tourniquet test result
10 or more petechiae per 1 square inch
what is the tourniquet test used to diagnose
dengue fever
what is the treatment for dengue fever
eure patient stays well hydrated and avoid aspirin containing drugs/NSAIDS
Avoid invasive procedures such as NG tube intubations, IM injections, arterial punctures
- treat symptomatically
patients who have mild dengue fever, what is their disposition?
MEDEVAC.
for severe, med advice on further management while waiting for the medevac
Patient reports to medical following his return from leave. He recently went home to Arizona and reports he was camping for about 3 days and believes he was bit by a tick because of a rash he has on his wrists, forearms, ankles and is starting to spread to his chest. He reports being febrile.
INSPECTION: small pink macules on wrists and forearms
what might be the cause
Rocky mountain spotted fever
what is the treatment for rocky mountain spotted fever
doxycycline 100mg BID for 5-7 days
how can you help prevent ticks?
treat gear and clothing with 0.5% permethrin
use EPA insect repellant (DEET)
Wear long pants, long sleeves, long socks.
- light colored clothing also helps identify ticks
perform tick checks at 12 hour intervals
Patient reports to medical after returning from a backpacking trip in europe. He reports having flu like symptoms such as malaise, headache, fever. But is mostly concerned about a red ring like rash that appeared one week after returning from leave.
PE: lymphadenopathy, Homogenous expanding rash and the present appears to have some facial drooping on the right side
what might this be
lyme disease
what is the causitive bacteria of lyme disease
B. Burgdorferi
what areas do ticks usually attach to?
any part but prefer the groin, axilla and scalp
in the late disseminated stage of lyme disease what is the presenting symptoms
same as acute but with rheumatologic manifestations
- transient, migratory arthritis and effusion in one or more joints
when would you NOT perform serologic testing for lyme disease
asymptomatic patient in endemic area
asymptomatic patient after an Ixodes tick bite
Patient with non specific symptoms (subacute myalgias, arthralgias, fatigue)
if performing a serolgic testing on a patient suspected to have lyme disease, what tests do you perform
acute/early disseminated: 2 ELIZA tests
LATE: 2 ELIZA or 1 ELIZA and 1 Western blot (shows specific antigens of B. Burgdorferi are reacting with serum antibody)
what is the treatment for lyme disease
early (Erythema migrans) 14 days of Doxycycline
early disseminated (bells palsy) 14 days of doxycycline
Late disseminated (arthritis) - 28 days of doxycycline
what can be used as a post-exposure prophylaxis for lyme
doxycycline 200mg PO 1 dose
prophylaxis can be started within what time frame of tick removal?
72 hours
what are the two subtypes of leishmaniasis
old world (eastern hemisphere)
new world (western hemisphere)
what are the predisposing factors of leishmaniasis
chronic sand fly exposure, poverty, proximity to dogs/cats/rodents
how is leishmaniasis trasnmitted
bite of infected female phlebotomine sand flies
what is the incubation period for leishmaniasis
2 weeks to several months and in cases up to 3 years; some >20 years
what is the most common manifestation of leishmaniasis
cutaneous leishmaniasis which is characterized by gradual onset cutaneous lesions
- begins as pink colored papule that enlarges to a plaque like lesion, lesion ulcerates with indurated border and may have thick white-yellow fibrous material
-lesions are often painless
how is cutaneous leishmaniasis diagnosed
clinicians maintain high suspicion in any patient with chronic (nonhealing) skin lesions
confirmed through lab confirmation and achieved by detecting the parasite or their DNA in infected tissue
lesions should be scraped gently with a sterile scalpel blade, lancet, or cytology brush
what is the treatment for cutaneous leishmaniasis
ulcer should be debrided and kept clean to avoid secondary infection
bandage and wrap
they need to go to infectious disease at some point
what medications can be used to treat cutaneous leishmaniasis
orally administered “azoles” and topical formulations for CL
what is the prevention for leishmaniasis
avoidance of being bitten by sand flies in endemic areas
- sleep in screened areas
- they feed at night
- less active at hottest time of day
- they dont buzz
- fans or ventilators
- spray quarters
- protective clothing and topical application DEET
what are the subtypes of methicillin-resistant staphylococcus aureus (MRSA)
community associated (CA-MRSA)
Health care associated (HA-MRSA)
what conditions predispose someone to MRSA
hospitals
prisons
close living quarters
military
athletes
weakened immune systems
patient presents to medical due a spider bite that has recently started “oozing” what might be the cause
MRSA
what is the treatment for MRSA
I&D is the mainstay therapy for any FLUCTUANT LESION, followed by proper packing of the wound.
ANTIBIOTICS:
- TMP-SMX
- Clindamycin
- Doxycycline
what are two basic categories of human bites
occlusive wounds - similar to dog or cat bites
clenched fist or fight bites - skin surface strikes a tooth
how are hand wounds examined
fingers extended and in the clenched fist position, wounds can often disappear with fingers in extension
what is the management of a fight bite if no signs or sx of infection present
- exam hand
- initial wound care is primary factor in preventing infection
- assess TDAP/HBV/HIV immz/testing status
- Eval for antibiotics prophylaxes and follow up in 24hr
- clinically uninfected? no culture
when would you close a human bite wound
if it involves the face and show no s/s of infection, less than 24 hours, and MO should be consulted
when would antibiotics be prophylactically recommended for human bites
- lacerations undergoing partial closure and wounds requiring surgical repair
- wounds on hands, face, or genital area
- wounds near a bone or joint
- wounds in areas of underlying venous or lymphatic compromise
- wounds in immunocompromised host
- wounds with associated crush injury
what antibiotics should not be used with MRSA suspected infection
cephalexin
penicillinase-resistant penicillins PRP (dicloxacillin)
macrolides (erythromycin/azithromycin)
what is the preferred antibiotics for early prophylaxis for a fight bite
amoxicillin clavulanate 875/125mg PO
what does osteomyelitis most often affect
vertebrae of the spine and or the hip
- among younger adults, OM occurs most commonly in the setting of trauma and related surgery
how does osteomyelitis present?
gradual onset of symptoms over several days
dull pain at site, with or without movement
systemic symptoms (fever, rigors) may also be present
what labs are ordered for someone suspected to have osteomyelitis
CBC may have leukocytosis
blood culture may be positive
ESR elevation
CRP elevation
what is an essential component in the evaluation of suspected OM
radiographic imaging
- plain radiograph is typically initial
- most useful are plain radiographs, magnetic resonance imaging, and technetium 99 bone scienitigraphy
what is an essential component in the evaluation of suspected OM
radiographic imaging
- plain radiograph is typically initial
- most useful are plain radiographs, magnetic resonance imaging, and technetium 99 bone scintigraphy
what is an essential component in the evaluation of suspected OM
radiographic imaging
- plain radiograph is typically initial
- most useful are plain radiographs, magnetic resonance imaging, and technetium 99 bone scintigraphy
what is the most common cause of acute OM
S. Aureus
what is the cornerstone of treatment for OM
prolonged antibiotic therapy
- IV Vancomyacin
- IV Ceftriaxone
what is the disposition of someone with OM
- patient needs to be MEDEVAC to higher level, surgical containment and IV antibiotics isnt possible on deployment
- confirmatory radiographs and studies required for definitive diagnosis
- MO should be contacted to determine starting empiric oral ABX prior to transport
what type of organism is tetanus
anaerobic, spore forming, gram positive bacterium
what are the predisposing factors of tetanus
inadequate TD immunization, no TD booster within 10 years, puncture wound, penetrating injury with foreign body (step on nail), untreated necrotic tissue, crushing injury
how is tetanus transmitted
direct contamination of open wounds and non-intact skin
- widely distributed in soil and the intestines and feces of farm animals
patient presents with trismus followed by nuchal rigidity, dysphagia, and rigid abdominal muscles. Patient was seen recently for a puncture wound but didnt know what caused the puncture. patient shows muscle spasms every 10-15 minutes. what might be the cause of the patients symptoms
tetanus
how may doses are in a tetanus series
3 doses
if the last documented TDAP was more than 5 years ago what will you do
administer booster of TDAP
what is the treatment for tetanus
immediate transfer to nearest MTF
clean/debride wound as best as possible
supportive therapy and airway protection
- ANTIBIOTICS = Metronidazole 500mg IV, Pen G 2-4mil units
what is inflammation of the meninges (dura mater, arachnoid mater, and pia mater)
meningitis
what is inflammation of the brain itself
encephalitis
A patient presents with fever, nuchal rigidity, altered mental status and a severe headache. What might be the cause
meningitis
what is the preferred imaging for someone suspected to have menigitis
CT
what is the lab required for diagnosis of meningitis
lumbar puncture
what is the foundational treatment for meningitis
manage airway
maintain oxygenation
sufficient IV fluids
control fever
- initiate empiric ABx and initiate MEDEVAC
- Ceftriaxone 2g IV or Pen G
administering what medication is associated with reduction in rate of hearing loss, neuro compromise and decreased mortality rates of meningitis
IV dexamethasone
if there are signs of ICP in meningitis , what can you do
elevate the head of the bed 30 degrees, induce mild hyperventilation in intubated pts and osmotic diuretics
what is given to close contacts of someone with meningitis
ceftriaxone 250mg IM one time
or
Ciprofloxacin 500mg PO one time
what is mononucleosis also known as
epstein barr virus
how is mono transmitted
body fluids, primarily saliva
what is the incubation period of mono
4-6 weeks
patient presents with a sore throat x 2 days and now has a fever and malaise.
Exam shows cervical lymphadenopathy and exudative pharyngitis. Another two sailors come in with the exact same symptoms, what might be the cause
mononucleosis
what is the treatment for mono
bed rest, acetaminophen or nsaids
salt water gargles
avoid antivirals
SIQ TIL ACUTE SYMPTOMS SUBSIDE
LLD FOR 3-4 WEEKS
What is the scientific name of rabies
lyssa virus
how does rabies present
pain and paresthesia at the site is often first sx
- fever, hydrophobia, pharyngeal spasm, hypersalivation, lacrimation, goose flesh and dilatated pupils
- lose of DTR and Plantar reflexes
what is aerophobia
pathognomonic pharyngeal muscle spasms triggered by feeling draft or air, leads to aspiration, coughing, choking
how is diagnosis of rabies confirmed
post-mortem evaluation of the brain