ICR Gyn Stuff Flashcards

1
Q

Compare the epithelium of the Vagina vs. the Vulva

A

The vulva and vagina are lined with squamous epithelium. The vulva contains keratinized epithelium, and is hair-bearing. The vagina is onkeratinized,and is nonhair-bearing

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2
Q

What epithelium do we see in the cervix, and what is the zone of metaplasia?

A

-The cervix contains glandular and squamous epithelium. This zone of metaplasia is a common origin for cervical dysplasia and is what is screened with cervical cytology.

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3
Q

What is bacterial vaginitis and how does it present?

A
Bacterial vaginitis (BV) is the most common vaginitis, responsible for 50% of
vaginitis. BV presents clinically with malodorous vaginal discharge that has a pH greater than 4.5. Clue cells are observed on a saline wet mount.
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4
Q

What is yeast vaginitis and how does it present?

A

Yeast vaginitis accounts for 25% of vaginitis. Yeast vaginitis presents clinically with itching and irritation, and a thick curd-like non-odorous discharge. pH is between 4 and 5. Budding yeast and hyphae are observed on a KOH smear

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5
Q

What is Trichomonas Vaginitis and how does it present?

A

Trichomonas vaginitis accounts for 25% of vaginitis. Trichomonas presents
clinically with a greenish vaginal discharge, nonodorous, and motile flagellated trichomoads are observed on a saline wet mount.

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6
Q

What are combination hormonal contraceptives and what are some examples?

A

Combination hormonal contraception includes oral (oral contraceptive pills or OCP’s), transdermal (Ortho Evra), or vaginal (Nuva Ring) routes of administration. Combination hormonal contraception works by suppressing ovulation, creating a thick cervical mucus barrier, and thinning the endometrium and affecting tubal transport. Failure rates are

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7
Q

Complications of IUDs

A

Potential complications include uterine perforation, infection, and expulsion

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8
Q

What is a cystocele and how does it present?

A

Cystoceles form when the bladder prolapses against a weakened anterior vaginal wall. Symptoms may include bulging, inability to empty bladder

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9
Q

What is a rectocele and how does it present?

A

Rectoceles form when the rectum prolapses against a weakened posterior vaginal wall. Symptoms may include bulging and pressure, an inability to defecate, and a need to place finger into the vagina and push posteriorly to
assist with bowel movements (splinting)

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10
Q

What is a cervical and uterine prolapse and how does it present?

A

Cervical and uterine prolapse occur when there is a loss of structural support of the uterus, particularly of the uterosacral and cardinal ligaments.

Symptoms include bulging, pressure, and low back pain

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11
Q

What is urge incontinence and how do we treat it?

A
Urge incontinence (also referred to as “overactive bladder”) is a result of
detrusor overactivity, resulting in a sensation of frequency and urgency, with loss of large volumes of urine associated with a sensation of needing to void.

Treatment is with anticholinergics to reduce detrusor contractions

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12
Q

What is stress incontinence and how do we treat it?

A

Stress incontinence is a result of loss of urethral support, resulting in hypermobility of the urethra. Symptoms include leakage of small amounts of
urine associated with an increase in abdominal pressure, or Valsalva maneuvers. Patients complain of leakage of urine with cough, sneeze, laugh,
jumping, or exercising.

Treatment may be with Kegel exercises, pessary, or
surgical.

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13
Q

What is overflow incontinence and how does it present? How do we treat it?

A

Overflow incontinence results from neurologic insult and an inability to sense that the bladder is full. Patients report continuous leakage or constant dribbling, and usually have a history suggesting potential for neurologic insult. Treatment may require intermittent self-catheterization.

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14
Q

What is intrinsic sphincter deficiency and how does it present?

A

Intrinsic Sphincter Deficiency results from a loss of urethral sphincter function. Symptoms may be similar to stress incontinence, but the patient may not exhibit hypermobility of the urethra.

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15
Q

What is endometriosis?

A

Endometriosis results from endometrial glands and stroma implanted in areas outside of the endometrium

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16
Q

How do we treat endometriosis?

A

Endometriosis is treated by suppressing endometrial activity, with combination contraception, gonadotropin releasing hormone agonists, or
22:14 surgically by ablating endometrial implants. More drastically, both ovaries
can be removed, resulting in no further estrogen production. Low dosage HRT usually must be provided back to the patient, though, to protect bone health.

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17
Q

Function of Clomid (clomiphine

citrate)

A

Induces ovulation, possible treatment for infertility caused by anovulation.

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18
Q

Why might we do a myomectomy on a patient who is infertile?

A

Myomectomy can be done to remove intrauterine fibroids that are causing a mass effect in the uterine cavity preventing pregnancy.

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19
Q

What do we mean by “Estrogen, unopposed?”

A

Estrogen, unopposed: The continuous and prolonged effect of estrogen on the
endometrium, resulting from a lack of progesterone. This is associated with an
increased risk of endometrial cancer.

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20
Q

Urethrocele?

A

Urethrocele: Protrusion of the urethra through the supporting structure of the anterior
vaginal wall.

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21
Q

Thelarche?

A

Thelarche: The onset of development of breasts.

22
Q

Thecoma?

A

Thecoma: A functioning ovarian tumor composed of theca cells which produces
androgens (testosterone).

23
Q

Withdrawal bleeding?

A

Withdrawal bleeding: Uterine bleeding after the interruption of hormonal support of the endometrium, typically obtained after a 10 day treatment with progesterone.

24
Q

How do we do Schiller’s test and what does it indicate?

A

Schiller test: The application of a solution of iodine to the cervix. The iodine is taken up by the glycogen in normal vaginal epithelium, giving it a brown appearance. Areas lacking in glycogen are white or whitish yellow, as in leukoplakia or cancer.

Although nonstaining areas are not diagnostic of cancer, they aid in choosing the spot
to which a biopsy should be directed.

25
Q

What is a Salpingooophorectomy?

A

Salpingooophorectomy: Surgical removal of a fallopian tube and ovary.

26
Q

Salpingostomy?

A

Salpingostomy: Surgically incising the lumen of the fallopian tube in order to
remove its contents (i.e. blood or ectopic pregnancy).

27
Q

Delayed vs. Precocious puberty

A

Delayed: The lack of appearance of secondary sexual characteristics by age 14.

Precocious: The appearance of secondary sexual characteristics before 7.5 years of age.

28
Q

Polymenorrhea?

A

Polymenorrhea: Cyclical uterine bleeding that is normal in amount, but occurs

29
Q

Pessary?

A

Pessary: A device placed in the vagina to support the uterus and pelvic floor

30
Q

Perineorrhaphy?

A

Perineorrhaphy: Reconstructive repair of the perineum where the perineal body is rebuilt by reapproximating the Transverse Perineii muscles, the Bulbocavernosis muscles and the External Anal Sphincter.

31
Q

Metrorrhagia?

A

uterine bleeding occurring completely irregularly at frequent intervals, amount variable

32
Q

Menorrhagia?

A

prolonged or excessive uterine bleeding > 7 days occurring at regular intervals, or >80 ml

33
Q

Uterosacral vs cardinal ligaments

A

Cardinal: The dense connective tissue that represents the union of the base of the broad ligament to the supravaginal portion of the cervix and laterally to the sides of the pelvis. It is considered to be the primary support of the uterus.

Uterosacral: The peritoneal folds containing connective tissue, autonomic nerves and involuntary muscle arising on each side of the posterior wall of the uterus at about the level of the internal cervical os and passing backward toward the rectum, around which they extend to their insertion on the sacral wall. It is considered to play an important part in axial support of the uterus.

34
Q

What makes up the Levator Ani and what is its purpose?

A

Levator Ani Muscle: The muscular sheet, consisting of the iliococcygeus, pubococcygeus and puborectalis muscles, which forms most of the pelvic floor (pelvic diaphragm) and supports the pelvic viscera.

35
Q

Impotence?

A

Impotence: The inability to achieve or sustain penile erection

36
Q

Imperforate hymen?

A

Imperforate hymen: Failure of a lumen to develop at a point where the budding vagina arises from the urogenital sinus. Although the hymen may not be broken down at all, patients often still have a vagina.

37
Q

Abdominal hysterectomy

A

Abdominal (TAH): The removal of the uterine corpus and cervix through an incision made in the abdominal wall.

38
Q

Radical hysterectomy?

A

Radical: The removal of the uterine corpus, cervix and parametrium, with dissection of the ureters; usually combined with pelvic lymphadenectomy.

39
Q

LAV hysterectomy?

A

Laparoscopic Assisted Vaginal Hysterectomy (LAVH): The combination of laparoscopy with vaginal surgery techniques to remove the uterus, cervix, and, frequently, the adnexa.

40
Q

Subtotal hysterectomy?

A

Subtotal (supracervical): The removal of the uterine corpus, leaving the cervix in situ

41
Q

Total hysterectomy?

A

Total: The removal of the uterine corpus and cervix (without regard to tubes or ovaries).

42
Q

Vaginal hysterectomy?

A

Vaginal (TVH): The removal of the uterus and cervix through the vagina

43
Q

TL hysterectomy?

A

Total Laparoscopic Hysterectomy: The entire hysterectomy is performed via laparoscopy. The uterus may be removed either vaginally (via colpotomy) or morcellized and removed with a laparoscopic instrument. The vaginal cuff may be closed laparoscopically or vaginally.

44
Q

When does LH peak and how is this helpful?

A

LH peaks day 14, thus LH can be used to predict ovulation

45
Q

When is FSH up?

A

FSH slightly increased day 14 and 27-28

46
Q

When does Estradiol peak?

A

Estradiol peaks day 12-13

47
Q

When does Progesterone peak?

A

Progesterone peaks day 18-22 then falls

48
Q

When does Inhibin increase?

A

Inhibin increased in luteal phase

49
Q

What are the three stages of the endometrium?

A

Menstrual Endometrium
Proliferative phase Endometrium
Secretory Phase Endometrium

50
Q

Discuss the menstrual endometrium

A
  • Thin, dense , nonfunctioning basalis
  • Small residual stratum spongiosum
  • ~2/3 of functioning endometrium lost during menses
51
Q

Discuss the proliferative phase endometrium

A
  • Period of increased estradiol secretion secondary to follicular development
  • Glands increase in number, link together with bridges
  • Thickness increases to ~ 5 mm
52
Q

Discuss the secretory phase endometrium

A
  • Height fixed despite continued estrogen secretion secondary to progesterone secretion. Progesterone functions as a stabilizing agent.
  • Individual components keep growing but are confined in a fixed structure leading to more tortuosity of glands and vessels