ICPP S1 Thermoregulation And Homeostasis Flashcards

1
Q

Define homeostasis.

A

The maintenance of an internal environment, in a constant state, despite external changes.

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2
Q

What are some things that need to be controlled in order to maintain homeostasis?

A
  • Temperature
  • pH concentration
  • Oxygen concentration
  • CO2 concentration
  • Electrolyte levels
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3
Q

What are the 3 main components of a homeostatic system?

A

Receptors.
Control center
Effectors

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4
Q

Define thermoregulation

A

The control/ maintenance of a constant internal temperature.

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5
Q

Define core temperature.

A

The temperatures of the internal environment and internal organs.

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6
Q

What are the 2 types of skin themoreceptors?

A

Skin thermoreceptors and hypothalamic thermoreceptors.

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7
Q

Where do skin thermoreceptors signal?

A

These sensory receptors send signals to the hypothalamus’ pre-optic area (POA), specifically the thermoregulatory centre in the hypothalamus.

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8
Q

What are the physiological responses to increased core temperature?

A

Increased cutaneous blood flow - vasodilation.
Increased rate of sweating
Hairs lie flat.

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9
Q

What are the physiological responses to decreased body temperature?

A

Decreased cutaneous blood flow through vasodilation.
Shivering - skeletal muscle contraction.
Hairs stand on ends.

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10
Q

What is the normal core temperature range?

A

36.5 to 37.5

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11
Q

As levels of hyperthermia increase at what temperature ranges can we start to classify the following:

  • Clinical onset of hyperthermia
  • Hyperthermia
  • Hyperpyrexia
A

Clinical onset
37.5-38.3

Hyperthermia
38.3-41

Hyperpyrexia
40-41

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12
Q

As levels of hypothermia decrease at what levels can we classify the following:

  • Mild hypothermia
  • Moderate hypothermia
  • Severe hypothermia
A

Mild Hypothermia
32-25

Moderated hypothermia
32-28

Severe hypothermia
<28

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13
Q

Why may elderly people have trouble with thermoregulation?

A

Gradual decline in body function leads to:

  • Reduction in function of cardiopulmonary, renal and MSK systems.
  • Decreased ability to synthesis NTs - adverse effects on CNS and PNS.
  • Decreased sweat response.
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14
Q

Why do neonates and infants have problems with thermoregulation

A
  • Immature body systems
  • No thermogenesis shivering reflex
  • Limited effects of vasoconstriction
  • Excessive sweating will cause fluid loss at higher temperatures.
  • Large SA:V - rapid heat loss.
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15
Q

What do neonates and infants rely on for thermoregulation?

A

Non-shivering thermogenesis.
Large amounts of brown adipose tissue, highly vascular and high rate of metabolism.
Lots of exergonic reactions in the BAT to release high.

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16
Q

What is multiple sclerosis?

A

MS involves demyelination of nerves in the CNS.

17
Q

Why do people with MS have trouble with thermoregulation?

A

Thermoregulatory pathways will be affected therefore there will be blocks in signal conduction, effecting sweat response, vasoconstriction and shivering.

18
Q

Why do people with diabetes have problems with thermoregulation?

A

Reduced metabolism of glucose results in lowering of temperature.
Peripheral nerves can lose functionality because of effects on circulation.
Reduced blood flow and decreased sweating response.