ICP-MS Flashcards
1
Q
Advantages of ICP-MS over ICP-OES?
A
Wider element coverage
EXTREMELY LOW LOD
Interference removal technology
2
Q
Features of Mass Spectrometry
A
High sensitivity
simultaneous multi-element analysis
large calibration ranges
isotope ratio measurements
3
Q
Basic Schematic of ICP-MS
A
Sample -> ICP -> Quadrupole -> Detector
4
Q
Two General Types of Interferences?
A
Spectral: Interferences formed from combination of plasma gases and sample matrix constituents
Non-spectral: signal suppression and enhancement effects. can be overcome by using internal standards.
5
Q
Three types of spectral interference?
A
Isobaric Overlap - Equal mass isotopes of different elements
Polyatomic interferences - Simple molecular ions with same mass as analyte
Doubly ionised species - Not much of a problem
