ICP L6: Enamel homeostasis and caries development Flashcards

1
Q

How can loss of tooth mineral occur

A
  1. caries
  2. gustatory acids
  3. dietary sources
  4. erosion
  5. mechanical wear; attrition, abrasion, abfraction
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2
Q

What is caries

A

Loss of tooth substance by metabolically produced acids, it is a bacterial disease and involves molecular level interactions between bacterium and sugars

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3
Q

Define primary caries

A

Lesions on unrestored surfaces

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4
Q

Define secondary caries

A

Recurrent lesions adjacent to fillings ocuring marginally

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5
Q

Define residual caries

A

Demineralised tissue left behind before a filling has been placed

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6
Q

Define active caries

A

This is considered to be a progressive form

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7
Q

Define arrested caries

A

Considered a no longer progressive form

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8
Q

What is a white spot lesion

A

The first visible sign by naked eye - detected by shining bright white light; these are reversible and do not need surgical intervention

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9
Q

What is a brown spot lesion

A

An inactive white spot lesion discoloured by the uptake of dye from food debris

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10
Q

What is rampant caries

A

Multiple active carious lesions in the same patient (often linked to xerostomia)

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11
Q

What is hidden caries

A

Usually in dentine and only detectable by radiography (this means the lesion is large and so not reversible)

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12
Q

How can white spot lesions be differentiated from defects

A

Defects will not change in shape or size and so successive visits can be used to differentiate between these

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13
Q

What is the difference between an active cavitated and an active non-cavitated lesion

A

Non-cavitated is present on the tooth surface, cavitated white lesions go deeper into the underlying tooth material - this requires surgical intervention and so cannot be repaired naturally

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14
Q

What are cavitated lesions filled with

A

Dental plaque

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15
Q

Why do white lesions occur

A

Because there are micropores in the enamel surface as demineralisation has started; this scatters white light and so the white lesion is an optical phenomena for early caries detection

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16
Q

Outline the structure of a white spot lesion and describe where demineralisation occurs

A
  1. Surface layer
  2. Body of lesion
  3. Dark zone
  4. Translucent zone

Demineralisation occurs at the subsurface level meaning the outer enamel surface is still intact

17
Q

What are the functions of saliva

A
  1. Neutralise acids so inhibit demineralisation and enhance remineralisation
  2. Recycle ingested fluoride in the mouth
  3. Discourage bacterial growth
  4. Contains proteins which sustain enamel surface
  5. Protect tissue
  6. Enhance taste
  7. Lubricates food and so increases oral clearance
  8. Digestion of carbohydrates
18
Q

Why is there a greater salivary concentration of Ca2+ in when the pH is lower

A

Because it is released from the salivary proteins to protect the teeth from acid attacks

19
Q

What are the causes of xerostomia

A
  • autoimmune
  • H+N radiotherapy
  • salivary gland disease
  • medication
  • aplasia of salivary glands
20
Q

Which drugs can cause iatrogenic xerostomia

A
  1. Dirutetics
  2. Anti-inflammatorys
  3. Anti-histamines
  4. Anti-epileptics
  5. Antihypertensives
  6. Tricyclic antidepressants
  7. SSRIs
  8. Antipsychotics
  9. Antihistaminics
21
Q

How is the stephan curve different for patients with xerostomia

A

It takes longer to return to a normal pH