IC2

Question 1

What does blood transport? (4)

Answer 1

1. Respiratory gases (O2, CO2)
2. Nutrients
3. Waste
4. Hormones (from glands -> target organs)

Question 2

What does blood regulate?

Answer 2

• Body temp
• pH of interstitial fluids
• ion composition of interstitial fluids

Question 3

What is hematocrit?

Answer 3

The relative volume of red blood cells out of the total blood volume

Question 4

What is the clinical meaning of a low hematocrit?

Answer 4

Anemia

Question 5

What could you tell from a high leukocyte count?

Answer 5

Infection, inflammation, cancer

Question 6

Function of RBC (erythrocytes)? (4)

Answer 6

• Respiratory gas transport
• Contains hemoglobin transport O2
• Contains carbonic anhydrase transport CO2
• Buffer pH in blood

Question 7

Hemoglobin consists of which 2 components? Elaborate

Answer 7

Globin and Heme

Globin: 4 folded polypeptide chains, 2a and 2b chains

Heme: protein, NOT pigment! Heme group contains 1 iron (Fe) which binds to 1 O2 molecule. Binding is WEAK, REVERSIBLE

Question 8

Each Hb molecule transports how many molecules of O2?

Answer 8

4

Question 9

Define polycythemia/ erythremia?

Answer 9

Too many RBC and high hematocrit

Question 10

What is hemostasis?

Answer 10

Processes aimed at closing a leak in the vascular system, to prevent loss of blood

Question 11

What are the 3 phases in hemostasis?

Answer 11

1. Vasoconstriction
2. Platelet plug
3. Fibrin clot

Question 12

What are the 3 phases in hemostasis?

Answer 12

1. Vasoconstriction
2. Platelet plug
3. Fibrin clot