IBS, Acute Diarrhea Flashcards
IBS age epidemiology
F>M
20-39 years
IBS presentation
Chronic/recurrent abdominal pain/discomfort
Cramping, diffuse lower abdominal pain→ variable intensity, periodic exacerbations
+/- dyspepsia, atypical chest pain, vomiting (rare)
IBS categories:
Constipation predominant
Diarrhea predominant
Mixed
Unclassified
Extraintestinal symptoms of IBS
Sexual dysfunction dysmenorrhea Irritative voiding symptoms Fibromyalgia somatic or psychological complaints
Rome IV criteria for IBS
Recurrent abdominal pain 1 or more days/week in last 3 months + 2 or more:
- Related to defecation
- Change in stool frequency
- Change in stool form
IBS, C/D alarm symptoms
Onset >50 years Severe/progressively worsening Nocturnal diarrhea Fevers/vomiting Unexplained weight loss Melena, hematochezia, (+) occult blood Personal or family history of colon cancer, IBD, Celiac Iron deficiency anemia
Labs for IBS
Not usually indicated \+/- CBC, CMP, TSH ESR/CRP Celiac serologies stool studies
Further workup for IBS is indicated in cases of…
Atypical history
alarm features
refractory
Further workup for concerning IBS cases includes
Laboratory/stool studies
Cross sectional/small bowel imaging
Endoscopy/colonoscopy with biopsies
How much fiber should an IBS patient be taking?
20-35 g daily→ start low, increase slowly
Diet for IBS
FODMAP diet:
Eliminate sugars and fibers that cause pain and bloating
Eliminate x 4-8 weeks→ gradually reintroduce 1-2 foods at a time→ assess tolerance
Trained dietician to avoid unnecessary over-restriction, may not be appropriate for everyone
Levsin
anticholinergic for abdominal pain
Bentyl
anticholinergic for abdominal pain
Side effects of anticholinergic meds
Dry eyes
Dry mouth
Constipation
Rifaximin
Diarrhea meds
Imodium
Diarrhea meds
Alosetron
Diarrhea meds
Viberzi
Diarrhea meds
Which diarrhea med can only be prescribed to women and needs a risk management program?
Alosetron
Psychosocial meds for IBS
TCAs
Evaluate for _____ on DRE (for constipation)
evaluate for fissures hemorrhoids tenderness, masses stool anal stricture anal sphincter tone perineal descent dysynergic defecation
Rx agents for constipation side effects
Diarrhea
Lubiprostone
Rx agent for constipation
can cause diarrhea
Linaclotide
Rx agent for constipation
can cause diarrhea