IBS

Question 1

Spreading Proximal meaning?

Answer 1

Spreading upwards towards the centre

Question 2

Spreading distally meaning?

Answer 2

Moving away towards rectum

Question 3

Cause of IBD?

Answer 3

idiopathic cause by immune response to intestinal microflora
–> autoimmune
–> strong genetic link

Question 4

UC description?

Answer 4

chronic inflammatroy condition characterized by episodes of inflammation limited to the mucosal layer of the colon
–> Relapse remitting pattern
–> limited to the colon (starts in rectum and spreads proximally)

Question 5

CD description?

Answer 5

chronic transmural inflammation with SKIP LESSIONS, affecting mouth to perianal area
–> can have relapse remission but not as common as UC
–> most common start spot is in illeum or proximal colon

Question 6

Is there perianal involvement in UC or CD?

Answer 6

Never for UC
Rare for CD

Question 7

Is there rectal sparing in UC or CD?

Answer 7

Never in UC
Common in CD

Question 8

Complication development more common in UC or CD?

Answer 8

CD

Question 9

Peak onset of IBD?

Answer 9

15-40 years of age

Question 10

Risk factors of IBD?

Answer 10

age (15-40)
male = female
genetic influence
poor diet (high in fat, omega 3 useful in IBD though, to much Omega 6 or 9 may cause flares)
smoking??? (helpful for UC harmful for CD)
obesity
sedentary lifestyle
Stress
Med:
- Antibiotics
- NSAIDs

Question 11

Symptoms of IBD?