IBD, coeliac, UC Flashcards
Treatment for acute UC? (2021- NICE)
Mild-Mod:
1st line -> Rectal (topical) Mesalazine or 5asa
Extensive colitis (left sided): 1st line -> Rectal + Oral Mesalazine
Acute Severe disease:
Admit, IV hydration, NBM
IV hydrocortisone or Methylpred
maintenance Treatment for UC? (2021- NICE)
mild-mod (proctitis or proctosigmoiditis): Rectal mesalazine
extensive colitis/left sided: Oral mesalazine
mx chrons?
1st - PO prednisolone
Maintaining remission:
+ Azathioprine/Mercaptopurine
Infliximab/Adalimumab - if severe.
Distal ileal, ileocaecal or right-sided colonic disease - acute;
- Budesonide if cant use normal steroid
risk of surgery in crohns vs UC?
50-70% risk surgery (though surgery not curative, as other parts of tract can be impacted)
30% in UC
risk of cancer in UC vs crohns
higher risk colon cancer in UC
2 skin signs in IBD?
pyoderma gangrenosum
erythema nodosum
how does toxic megacolon present?
hisotry of bloody stools (UC sx)
distended abdomen
toxic signs; fever, shock - hypotension, tachycardia, abdo pain
management of toxic megacolon?
abdo xray - dilated colon >6cm
surgery - colectomy
causes of subtotal villous atrophy?
Coealiac
tropical sprue (hx coming back from tropics on holiday)
whipples - PAS +ve (periodic acid shift)
giardiasis
infectious diarrhoea
mx for tropical sprue?
Doxycycline
side effects of PPIs eg omeprazole?
osteoporosis
hypophosphotaemia
