IBD

Question 1

what dz characterized by transmural mucosal inflammation

Answer 1

chrons dz

Question 2

Crohn sx hallmarks

Answer 2

diarrhea (can bleed), + FOBT, abd pain RLQ, weight loss, low grade fever, fatigue, in peds see growth dealy

Question 3

crohn surg

Answer 3

1. 80% if sx refractory, obstruction or perf
2. medical: TPN, antispasmodics, antidiarrheals, 5-ASA drugs (Sulfasalasine or mesalasime
3. other med options: ciprofloxacin, metronidazole, cortiocsteriods for active dz
4. biologics- anti TNF therapies, anti integrins

Question 4

5 areas can see extraintestinal manifestations

Answer 4

1. eye - uveitis, iritis, episcleritis,
2. skin: pyoderma gangrenosum
3. peripheral arthritis:
4. sclerosing cholangitis:
5. thromboembolism (uncommon) - venous and arterial

Question 5

sclerosing cholangitis

Answer 5

fibrosis of bile ducts, leading to fever, pain, jaundice episodes