IBD Flashcards by Georgia Lamb | Brainscape

Q

Types of IBD

A

Chrons- affects any part of GI
Ulcerative colitis- only affects large intestine
Some overlap may exist

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Q

IBD epidemiology

A

Chrons- M:F 1:1.2
Ulcerative colitis- M:F 1.2:1

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Q

IBD aetiology

A

Genetic
Local enviro
Immune response

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Q

IBD pathogenesis

A

Familial
Genetic
Enviro
Nutritional
Smoking
Gut flora

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Q

Chrons clinical features

A

Diarrhoea
Abdominal P
Weight loss
Lack of energy- nutrients not being digested properly
Mouth sores
May present as emergency- massive flare up, e.g., vomiting

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Q

Chrons investigations

A

Blood tests- anaemia, raised ESR
Imaging- colonoscopy, ultrasound, spiral CT

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Q

Chrons management

A

Pharmacological- corticosteroids, B!2 and folic acid
Surgical- 80% will need it, ileostomy

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Q

Chrons prognosis

A

Wide variation
Approx 12% are chronic

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Q

Ulcerative colitis

A

Results in mucosal ulceration and dilation of lumen
Inflammation confined to mostly mucosal layer
Granulomas are rare

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Q

Ulcerative colitis

A

Bloody diarrhoea
Abdominal cramps
Severe P in rectum
Anaemia
Fatigue
Fever
Weight loss

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Q

Ulcerative colitis investigations

A

Blood tests- ESR and CRP raised, anaemia, raised WBC
Imaging- colonoscopy, radionuclide

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