I&E Week 1

Question 1

How should you treat acne fulminans?

Answer 1

• Do oral course of prednisone followed by accutane

- You have to do prednisone first or accutane won’t work as well

Question 2

What are the antibiotic options for treating moderate to severe inflammatory acne?

Answer 2

• Minocycline, Doxycycline, Erythromycin

- Continue topical treatments

Question 3

Inheritance pattern, classification, signs and symptoms of phenylketonuria:

Answer 3

• Autosomal recessive
• Amino acid disorder
• Mental retardation if phenylalanine levels get too high
• Light colored skin (compared to family)
• “Mousy” urine odor
• Gait/posture abnormalities

Question 4

Inheritance pattern, classification, signs and symptoms of congenital hypothyroidism:

Answer 4

• 85% sporadic, 13% autosomal recessive, 2% transplacental
• Metabolic disorder
• Severe mental retardation
• Growth problems (cretinism)

Question 5

Inheritance pattern, classification, signs and symptoms of sickle cell disease:

Answer 5

• Autosomal recessive
• Anemic disorder
• Usually appears in early childhood but variable
• Hemolytic anemia, splenic sequestration, pneumococcal dz, acute chest syndrome, aplastic crisis

Question 6

Key words associated with G6PD

Answer 6

• Fava beans
• Heinz bodies
• Kernicterus

Question 7

Most common bleeding d/o of childhood:

Answer 7

Idiopathic thrombocytopenic purpura