Hypothalamic Suprasellar Tumors Flashcards
1
Q
What tumors are associated w/ hypothalamic suprasellar tumors?
A
Gliomas and Craniopharyngiomas
2
Q
What mutations are associated w/ hypothalamic suprasellar tumors?
A
WNT pathway mutations
B-catenin
3
Q
Are gliomas and craniopharyngiomas malignant or benign?
A
Benign
4
Q
Where do hypothalamic Suprasellar Tumors arise from?
A
Rathke pouch vestigial remnants
5
Q
What age groups do adamantinomatous and papillary gliomas/craniopharyngiomas fall into?
A
Adamantinomatous (children)
Papillary (adults)
6
Q
Adamantinomatous morphology?
A
Palisading squamous epi on periphery
Wet keratin
Cysts w/ “machine” oil fluid
Calciications
7
Q
Papillary morphology?
A
Lack keratin and cysts
No palisading along periphery
