Hypothalamic and pituitary hormones

Question 1

words ending in troph and trophin - what do they mean

Answer 1

means they are hormones

Question 2

What class are all the hormones of APG?

Answer 2

All peptide hormones

Question 3

what does GH do

Answer 3

major role in growth, particularly linear growth and also affects met

Question 4

what does prolactin do? what does high concentration of prolactin inhibit

Answer 4

• stimulates mammary glands to produce milk
• promotes growth and development of the breasts

high conc inhibits GnRH release

Question 5

what does ACTH do? what is the procursor glycoprotein called

Answer 5

Stimulates synthesis/release of cortisol

pro-opiomelanocortin (POMC)

Question 6

POMC can give rise to multiple products T/F?

Answer 6

TRUE

Question 7

What does TSH do

Answer 7

stimulates synthesis and release of thyroid hormones

Question 8

What does LH and FSH do?

Answer 8

LH- ovaries and testes (Leydig cells) - stimulates steroid hormone synthesis (f: causes ovulation/formulation of corpus luteum

FSH - ovaries: stimulate follicular development. testes - spermatogenesis

Question 9

What’s the difference between a tropic and trophic hormone

Answer 9

tropic - turning - affecting activity of an endocrine gland

trophic - feed,grow - promote growth, tissue integrity

Question 10

What are 3 actions of AVP

Answer 10

arginine vasopressin (AVP) or ADH

• blood vessels - vasoconstriction, via V1 receptors at high AVP
• kidney (DCT and CD) - increase permeability and hence reabsoprtion of water via v2
• stimulate ACTH release

Question 11

What are 3 actions of oxytocin

Answer 11

stimulate ‘milk let down’, expression of breast milk

• uterine smooth muscle - contraction
• maternal behaviour/sexual behaviour