Hypopituitarism Flashcards
What type of cells does the
1. anterior pituitary
2. posterior pituitary
have?
- endocrine
2. neural
What are the 5 hormones released by the anterior pituitarry?
TSH (thyroid stimulating hormone/ thyrotophin)
ACTH (Adrenocorticotrophic hormone/corticotrophin)
Gonadotrophins: FSH/LH (Luteinising hormone, follicle stimulating hormone)
PRL (prolactin)
GH - growth hormone/somatotrophin
What does the anterior pituitary need to function?
Hypothalamus (inc signals) and functional blood supply (the hypo-pit axis)
How do signals travel from hypothalamus to anterior pituitary?
Hypo releases releasing or inhibiting factors that travel down the pituitary stalk via the blood vessels which make up the hypothalamic-pituitary portal axis and are fenestrated/leaky. once at the anterior pituitary - stimulate specific anterior pituitary cells to release/inhibit the release of content.
What does growth hormone do?
Growth in children,
Psychosocial in adults
What does prolactin do?
Milk prod/ Lactation post-partum
What do LH and FSH do?
What does TSH do?
Stimulates Triiodothyronine (t3) and thyroxine (t4) in thyroid
What does ACTH do?
Cortisol prod in adrenal cortex
What can undergo Primary/secondary disease?
thyroid
adrenal cortex (cortisol)
gonads
What is primary disease
.when the gland itself fails
What is secondary disease?
when there is no signal from hypothalamus or anterior pituitary
What is primary hypothyroidism and what happens to hormones?
What is secondary hypothyroidism, what happens to hormones?
What is primary hypoadrenalism?
