Hyponatremia And IVF Flashcards

1
Q

Which kids are at a higher rush of hyponatremia and why?

A

Those conditions associated with an increased risk of non-physiological ADH secretion

  1. Neurological infections - meningitis, encephalitis
  2. Respiratory infections - pneumonia
  3. Certain medications - morphine
  4. Head trauma
  5. Peri- and post-operative
  6. nausea
  7. Pain and stress
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2
Q

In what situations is it appropriate to use hypotonic IVF?

A

Never

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3
Q

What are the symptoms of hyponatremia

A
N&V
Lethargy & decreased LOC 
Irritability
Headache  
Apnea
Seizures 
Coma
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4
Q

What monitoring should children on IVF have?

A

Before starting: electrolytes
Accurate ins and outs
Regular blood work - at least daily if children are at high risk of impaired renal excretion

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5
Q

In which situation would you use NaCl 0.45% versus 0.9%

A
  1. 9%:
    - no baseline electrolytes available
    - low normal sodium 135-137
    - generally preferred
  2. 45%
    - higher sodium 145-154
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6
Q

Why is ringers lactate not a great maintenance option?

A

Lack of glucose

Presence of lactate

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7
Q

Why do kids need glucose in IVF?

A

Because they have limited glycogen stores

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8
Q

What conditions are excluded from this statement?

A

Those with significant difficulty regulating electrolytes and fly us: cardiac conditions, renal conditions, burns
Children less than 1 month - difficulty excreting sodium

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9
Q

How much sodium is in 0.9% NaCl?

A

154 mmol/L

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10
Q

Which kids are at risk of hypernatremia and fluid retention with isotonic fluids?

A
Those with:
renal concentrating defects 
Severe dehydration 
Impaired ability to excrete Na
Prolonged fluid restriction
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11
Q

What is a biochemical risk of lots of isotonic fluid especially if given fast?

A

Hyperchloremic metabolic acidosis

But this has not been shown in the trials about IVF

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12
Q

How would you define acute hyponatremia?

What is the risk?

A

Decrease in Na

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13
Q

What are isotonic fluids?

Why are kids at a higher risk of cerebral oedema with isotonic fluids?

A

0.9% NaCl
Hypo is less than this

Bc of SIADH

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