Hyponatremia Flashcards
Evaluation
urine Na
serum Na
clinical staus
Nml urine Na
10-20 mEq/L
Nml serum Na
~ 280
2 X Na = 2 X 140 = 280
Urine Na distinguishes between?
renal from non-renal causes
Urine Na < 10 mEq/L
renal retention to compensate for extrarenal fluid loss
Urine Na > 20
renal salt wasting
problem with kidneys
Serum osmo 284-295 mosm/kg
isotonic hyponatremia / Pseudohyponatremia
Mgmt of isotonic hyponatremia / Pseudohyponatremia
cut down fat (d/t hyperlipidemia or hyperproteinemia)
no fluid restriction
Serum osmo <280
Hypertonic hyponatremia
‘state of water excess’
Assess if hypervolemic or hypovolemic
Serum osmo < 10 mEq/L
hypovolemic
- diarrhea
- dehydration
- emesis
Serum osmo 20
hypovolemic
Low volume, kidneys cannot conserve Na
- diuretics
- ACE inhibitors
- Mineralocorticoid deficiency
Hypervolemic, hypotonic hyponatremia
need to restrict water
- Edematous state
- CHF
- Liver disease
- Adv renal failure
Serum osmo > 290
Hypertonic Hyponatremia
Hypertonic Hyponatremia d/t:
- Hyperglycemia, usu. HHNK
Mgmt of hyponatremia
tx bases on cause
If hypovolemic: NS IV
Urine Na > 20, treat cause
If hypervolemic, restrict water
If symptomatic (n/v, ha, malaise): NS IV with loop diuretic
If CNS symptoms present, 3% NS IV with loop diuretics