Hypoglycemic agents Flashcards
Should metformin be discontinued before the day of surgery?
metformin does not need to be discontinued before the day of surgery Ann will not cause hypoglycemia during fasting periods of 1 to two days. There is no risk of lactic acidosis with metformin in patients with a functioning liver and kidneys.
For what conditions are alpha glucosidase inhibitors administered?
the medical treatment of insulin resistance and hyperglycemia in metabolic syndrome, type 2 diabetes, and obesity is usually achieved with oral hypoglycemic drugs including alpha glucosidase inhibitors, sulfonyluras, meglitinides, D-phenylalanine derivatives, diguanides, and thiazolidinediones.
How do alpha glucosidase inhibitors work?
decrease postprandial carbohydrate digestion and absorption at the intestinal brush border. By reducing absorption of starch, dextrose, and disaccharides, alpha glucosidase inhibitors blunt the rise of postprandial glucose
list the common side effects of alpha glucosidase inhibitors
flatulence, abdominal cramping, and diarrhea are side effects that frequently result from undigested carbohydrates that reach bacteria in the lower colon. With the exception of occasional increases in liver transaminases, alpha glucosidase inhibitors are considered non toxic.