Hypoglycemia

Question 1

Whipple’s Triad

Answer 1

Sx consistent with hypoglycemia + low plasma glucose with precise method + relief of symptoms after plasma glucose is raised

Question 2

First defense against hypoglycemia

Answer 2

Decrease in Insulin secretion

2nd: Glucagon; 3rd: Epinephrine

Question 3

Stimulates hepatic glycogenolysis

Answer 3

Glucagon

Question 4

Stimulates hepatic glycogenolysis and hepatic and renal gluconeogenesis

Answer 4

Epinephrine

Question 5

Physiologic response to decreasing plasma glucose concentrations

Answer 5

Dec Insulin (80-85 mg/dL)
Inc Glucagon (65-70 mg/dL)
Inc Epinephrine (65-70 mg/dL
Inc Cortisol and GH (65-70 mg/dL)
Symptoms (50-55 mg/dL)
Dec cognition (<50)

Question 6

Blocks gluconeogenesis but not glycogenolysis

Answer 6

Ethanol (thus alcohol-induced hypogly occurs after several days)