Hyperuricaemia and Gout

Question 1

How are acute attacks of gout usually treated?

Answer 1

By high doses of NSAIDs. If the pain and swelling does not improve one may be given steroids as tablets or an injection.

Question 2

What can be used to treat acute attacks of gout when NSAIDs are contraindicated or not tolerated?

Answer 2

Colchocine.

Question 3

What is gout?

Answer 3

Gout is a type of arthritis that causes sudden, severe joint pain. This results from an excess of uric acid in the blood and tissues of the body, which if present for long enough, can form into needle-like crystals which can inflame your joints and cause severe pain and swelling.

Question 4

Which simple painkiller is not indicated for use in the treatment of gout?

Answer 4

Aspirin.

Question 5

Which drugs are used for long term gout control?

Answer 5

Allopurinol or febuxostat (if allopurinol is contraindicated).

Question 6

Use of febuxostat is associated with a risk of serious hypersensitivity reactions including SJS and acute anaphylaxis shock. What should patients be advised to look out for?

Answer 6

Signs and symptoms of severe hypersensitivity.

Question 7

What should be done if hypersensitivity to febuxostat is seen?

Answer 7

Treatment should be stopped ASAP.

Question 8

When do most cases of febuxostat hypersensitivity occur?

Answer 8

During the first month of treatment.