Hypertention Flashcards

0
Q

ACEI :ทำให้เกิดอะไร

A
Angiotensin 1เพิ่ม
Angiotensin 2 ลดลง
>>vasodilated
>>Aldosterone ลดลง
Bradykinin เพิ่ม>>ไอ
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1
Q

Enalapril

A

ACEI

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2
Q

Lasartan

A

ARB

@angiotensin2type1receptor

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3
Q

Aliskiren

A

Renin inhibit

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4
Q

Hydrochrolothyaside

A

Block @Na Cl exchange

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5
Q

Verapamil

A

Ca block @cardiac muscle

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6
Q

Diltiazem

A

Ca channel block @cardiac muscle

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7
Q

Amlodipine

A

Ca block @ vascular»vasodilated

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8
Q

Hypertensive emergency drug

A

Nifedipine

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9
Q

Propranolol

A

Nonselective beta blocker
»HR เพิ่ม
» vasoconstriction

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10
Q

Atenolol

A

Selective bete1block

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11
Q

Prozosin

A

Alpha 1 block

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12
Q

Terazosin

A

Selective alpha1. Blocker

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13
Q

Doxazosin

A

Selective alpha1blocker

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14
Q

Digoxin mechanism

A

Block @Na /K ATPase
เพิ่มCa ภายในcardiacmyocyte
เพิ่มduration @patua phase

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15
Q

Furosemide

A

Naลดลง
Kลดลง
Clลดลง

Ototoxicity

16
Q

Spironolactone

A

Aldosterone antagonist
Naลดลง.
Kเพิ่มขึ้น

17
Q

Amilorine

A

Diuretic drug

Block@ Na channel collecting druct

18
Q

Angina treatment

A
ลดdemand
; CCB BBs
เพิ่มsupply
; CCB nitrate
ลดthrombiosis
;antiplt , anticoagulant , fibrinolytic
19
Q

Isosorbide dinitrate/mono nitrate

A

(+)AG&raquo_space;> เพิ่มcGMP

Vasodilated effect

20
Q

Anticoagulant

A

Indirect thrombin inhibitor ; heparin

Direct thrombin inhibitor; warfarin

21
Q

Heparin

A

(+) anti thrombin 3
Mornitor APTT
ไม่ผ่านรก

22
Q

Antidote heparin

A

Protea mine sulfate

23
Q

Warfarin

A

Inactivated Vit k
Monitor : PT
ผ่านรก

24
Antiplt
Aspirin ADP receptor GP 2b3aantagonist
25
Clopidogrei
ADP receptor inhibit
26
Abciximab
GP2b3a receptor antagonist
27
Fibrinolytic
Streptokinase Urokinase Reactive tissue plasminogen activator (+) PLASMIN
28
Amiodarone
Antiarrhythmic drug Block K channel > delay repolarization Tx: ventricular tracycardia Contraindication : thyroid disease
29
Digoxin
Tx: atrium fibrillation
30
Adenosine
Tx: supra ventricular tracycardia