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Phamacology > Hypertention > Flashcards

Hypertention Flashcards

0
Q

ACEI :ทำให้เกิดอะไร

A 
Angiotensin 1เพิ่ม
Angiotensin 2 ลดลง
>>vasodilated
>>Aldosterone ลดลง
Bradykinin เพิ่ม>>ไอ
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1
Q

Enalapril

A

ACEI

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2
Q

Lasartan

A

ARB

@angiotensin2type1receptor

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3
Q

Aliskiren

A

Renin inhibit

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4
Q

Hydrochrolothyaside

A

Block @Na Cl exchange

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5
Q

Verapamil

A

Ca block @cardiac muscle

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6
Q

Diltiazem

A

Ca channel block @cardiac muscle

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7
Q

Amlodipine

A

Ca block @ vascular»vasodilated

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8
Q

Hypertensive emergency drug

A

Nifedipine

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9
Q

Propranolol

A

Nonselective beta blocker
»HR เพิ่ม
» vasoconstriction

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10
Q

Atenolol

A

Selective bete1block

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11
Q

Prozosin

A

Alpha 1 block

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12
Q

Terazosin

A

Selective alpha1. Blocker

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13
Q

Doxazosin

A

Selective alpha1blocker

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14
Q

Digoxin mechanism

A

Block @Na /K ATPase
เพิ่มCa ภายในcardiacmyocyte
เพิ่มduration @patua phase

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15
Q

Furosemide

A

Naลดลง
Kลดลง
Clลดลง

Ototoxicity

16
Q

Spironolactone

A

Aldosterone antagonist
Naลดลง.
Kเพิ่มขึ้น

17
Q

Amilorine

A

Diuretic drug

Block@ Na channel collecting druct

18
Q

Angina treatment

A 
ลดdemand
; CCB BBs
เพิ่มsupply
; CCB nitrate
ลดthrombiosis
;antiplt , anticoagulant , fibrinolytic
19
Q

Isosorbide dinitrate/mono nitrate

A

(+)AG&raquo_space;> เพิ่มcGMP

Vasodilated effect

20
Q

Anticoagulant

A

Indirect thrombin inhibitor ; heparin

Direct thrombin inhibitor; warfarin

21
Q

Heparin

A

(+) anti thrombin 3
Mornitor APTT
ไม่ผ่านรก

22
Q

Antidote heparin

A

Protea mine sulfate

23
Q

Warfarin

A

Inactivated Vit k
Monitor : PT
ผ่านรก

24
Q

Antiplt

A

Aspirin
ADP receptor
GP 2b3aantagonist

25
Q

Clopidogrei

A

ADP receptor inhibit

26
Q

Abciximab

A

GP2b3a receptor antagonist

27
Q

Fibrinolytic

A

Streptokinase
Urokinase
Reactive tissue plasminogen activator

(+) PLASMIN

28
Q

Amiodarone

A

Antiarrhythmic drug
Block K channel > delay repolarization
Tx: ventricular tracycardia
Contraindication : thyroid disease

29
Q

Digoxin

A

Tx: atrium fibrillation

30
Q

Adenosine

A

Tx: supra ventricular tracycardia

Phamacology (2 decks)

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