Hypertensive Emergency Flashcards
Which 2 drugs are used for Hypertensive Emergency?
Nitroprusside and Fenoldapam
What molecule involved in aerobic respiration can be blocked in Cyanide Toxicity?
Cytochrome C Oxidase aka Complex IV.
Which two toxicities block Cytochrome Oxidase C?
Cyanide and Carbon Monoxide
What are Sxs of Cyanide Toxicity?
Altered mental state, HA, N/V, Coma/Seizures
What is the treatment for Cyanide toxicity?
Sodium thiosulfate.
Which receptor does Fenoldapam act on and where?
D1 receptor in coronaries, peripheral, renal, splanchnic beds. Causes massive immediate decrease in blood pressure.
When is Fenoldapam indicated?
Hypertensive crisis or post-op HTN.
When is Fenoldapam contraindicated?
Hypotension, Natriuresis. Can also cause reflex tachycardia.
Which drugs are preferred in HTN emergency if pt has acute renal failure?
hypertensive emergency and acute renal failure are clevidipine, fenoldopam, and nicardipine.
