Hypertensive Drugs

Question 1

Atenolo

Answer 1

Beta 1 blocker. Reduces heart rate and heart contractility, decreasing BP.

Question 2

Bendroflumethiazide

Answer 2

It’s a diuretic. Causes excess urination, leading to a decrease in blood volume; hence, it reduces blood pressure.

Question 3

Ramipril

Answer 3

This is an angiotensin converting enzyme inhibitor. It prevents the production of angiotensin 2 and consequently aldosterone, which reduces BP.

Question 4

Angiotension 2

Answer 4

It increases BP, by binding to 1 or 2 of G coupled protein receptors ( AT1 and AT2( but more in the AT1).

Question 5

Increases BP by;

Answer 5

1. Causing vasoconstriction in the arterioles
2. Increasing the reabsorption of sodium
3. Increasing the release of noradrenaline through the sympathetic nervous system pathway.
4. Stimulating the release of aldosterone through the kidneys
5. Stimulates thirst sensation and increases the release of anti-diuretic hormone.

Question 6

Other drugs like Rmipril are

Answer 6

1. Isinopril
2. Enalapril

Question 7

Verapamil

Answer 7

It’s a calcium channel blocker. Used to treat blood pressure, angina, and superventricular tachycardia

Question 8

Amlodipine

Answer 8

Calcium channel blocker

Question 9

Propranolol, carvedilol

Question 10

Nifecard

Answer 10

Contains nefedipine, which is a calcium channel blocker