Hypertensive Disorders in Pregnancy Flashcards
What is the maternal complication of hypertensive disorders of pregnancy?
- end organ damage
What are the fetal complications of hypertensive disorders of pregnancy?
- prematurity
- growth restriction
- death
What is considered hypertension?
- greater than 140/90
** What are the 4 categories of hypertensive disorders of pregnancy?
- chronic hypertension
- preeclampsia/eclampsia
- chronic hypertension with superimposed preeclampsia/eclampsia
- gestational hypertension
** What is chronic hypertension? (TEST QUESTION)
- known hypertension prior to pregnancy or developing before the 20th week of gestation. This will be there at least 12 weeks (3 months) post partum.
What causes chronic hypertension?
- primary cause= “essential hypertension” (aka don’t know)
- secondary causes= metabolic disorders including renal disease, vascular disease, and endocrine disorders. Stress of pregnancy may bring out the fact that this woman is a chronic hypertensive.
** How do we manage chronic hypertension?
- obtain labs: CBC, BUN, creatinine, LFTs, 24 hr urine for protein and creatinine, urinalysis.
- EKG
- observe for superimposed preeclampsia
- observe for intrauterine growth restriction (IUGR).
- control BP between 140-150/90-100 (want it higher to ensure perfusion to baby bc it requires a high pulse pressure to get the blood to the baby).
- deliver at term if no complications
What percent of pregnant women with chronic hypertension will also get superimposed preeclampsia?
- 20%
*** Will pregnancy exacerbate chronic hypertension?
NO
** What is preeclampsia? (TEST QUESTION)
- NEW onset of HTN AND PROTEINURIA during latter half of gestation (after 20 weeks).
- greater than 140/90 at rest on 2 occasions in a sitting position 6 hrs apart.
- proteinuria greater than 0.3 g in a 24 hour urine collection.
- may be associated with edema, headache, visual changes, or epigastric pain.
If you were thinking preeclampsia, but it is sooner than 20 weeks, what should you think now?
Molar pregnancy
*** What are the 2 categories of preeclampsia?
- MILD
- SEVERE= severe HTN (systolic greater than 160 or diastolic 110 mm Hg) at rest, on 2 occasions at least 6 hours apart + heavy proteinuria (at least 5 g in a 24 hr collection or a qualitative value of 3+ in urine samples collected 4 hrs apart).
What will you see with SEVERE preeclampsia? (think what happens when your vessels clamp down)
- cerebral or visual disturbances
- pulmonary edema or cyanosis
- RUQ pain
- impaired liver function (elevated LFTs)
- thrombocytopenia
- fetal growth restriction
*** What is eclampsia?
- new-onset of TONIC-CLONIC SEIZURES in a woman with preeclampsia
- most happen during labor, but can happen before or after as well.
** What is chronic hypertension with superimposed preeclampsia?
- chronic hypertension with new-onset proteinuria (greater than 0.3 g in a 24 hr collection) after the 20th week of gestation.
** What is gestational hypertension? (TEST QUESTION)
- post partum diagnosis.
- defined as HTN occurring after the 20th week of gestation WITHOUT proteinuria.
- may occur 48-72 hours post partum, but will resolve by the 12th post partum week.
*** What is HELLP syndrome?
- variation of severe preeclampsia:
- H= hemolysis
- EL= elevated liver enzymes
- LP= low platelets
- BP may be initially normal, mildly elevated or severely elevated. Important to recognize HELLP and treat them as if they have severe eclampsia.
In what pts do you see HELLP most often?
- multiparous (have had multiple babies)
- greater than 25 years old
- less than 36 weeks gestation
What is the causes of preeclampsia?
- unknown, but likely genetic and involving the placenta and membranes.
- UTEROPLACENTAL ISCHEMIA definitely is a cause.
** What is the management for preeclampsia?
- if mild= observation with weekly non-stress tests or biophysical profiles.
- if severe= DELIVERY
What do you do if you need to deliver the baby due to preeclampsia and it’s less than 34 weeks?
give STEROIDS to help lung development
How do you manage intrapartum (during delivery) preeclampsia?
- MAGNESIUM SULFATE for seizure prophylaxis
- BP control with hydralazine or labetalol
How do you manage eclampsia (aka they are seizing)?
- maintain airway
- IV access
- Magnesium sulfate
- blood pressure recordings