Hypertensive And Diabetes Drugs Flashcards

1
Q

5 categories of anti hypertensive drugs?

A
  1. Diuretics
  2. B-blockers
  3. ACE- Inhibitors
  4. ARBs/Angiotensin Receptor Blockers
  5. Ca+ channel blockers
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2
Q

Diuretics 2 types?

A
  1. Loop
  2. K+ sparing
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3
Q

Diuretic examples (2)?

A

-azides aka hydrochlorothiazide (HCTZ)

Loop- fursomide or lasix

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4
Q

Side effects of diuretics?

A

Edema of ascites (fluid in the abdomen)

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5
Q

Angiotensin Receptors Blocker
ARB ending?

A

-sartan
Losartan

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6
Q

Beta Blockers ending?

A

-olol
Propranolol
Atenolol
Metoprolol

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7
Q

Angiotensin Converting Enzyme inhibitors aka
ACE Inhibitors ending?

A

-pril
Lisinopril
Enalapril

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8
Q

Ca+ Channel Blockers ending and examples?

A

-pine
Amlodipine
Nifedipine
One that doesn’t fit- diltiazem or verapamil

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9
Q

Types of diabetes medications?

A

Type 1- Insulin
Amylinomimetic

Type II
Oral Hypoglycemics
Incretin acting drugs
Dopamine agonists

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10
Q

Types of Insulin?

A

Short
Rapid
Intermediate
Long

And combination

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11
Q

Oral Hypoglycemic Diabetes Drug Types?

A

Biguanides
Sulfonylureas
Thiazolidinediones
Alpha-glucosidase Inhibitors

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12
Q

What diabetes drug do they not completely understand the MOA?

A

Dopamine agonist- Bromocriptine

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13
Q

Most popular diabetes oral hypoglycemic category and example?

A

Biguanides- Metformin

Also made in combinations

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14
Q

Biguanides MOA?

A

Decrease amount of sugar liver makes
Decrease sugar absorbed
Make body more sensitive to insulin
Help muscles absorb glucose

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15
Q

Oldest class of diabetes drugs, what category and suffix?

A

Sulfonylureas are a oral hypoglycemic

Suffix. -ide

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16
Q

Sulfonylureas MOA?

A

Stimulating the pancreas and beta cells to make more insulin

17
Q

What are Thiazolidinediones?
Suffix?

A

Oral hypoglycemics

-glitazone

18
Q

Thiazolidinediones MOA?

A

Decreasing glucose in liver
Help fat cells use insulin better

19
Q

What class of oral hypoglycemics increase risk of heart disease?

A

Thiazolidinediones

20
Q

2 classes of incretin acting diabetes drugs?

A

Glucagon-like peptides (incretin mimetics) (GLP)

And

DPP-4 Inhibitors

21
Q

GLP (glucagon like peptide) MOA and suffix’s?

A

Act like incretin by increasing beta cell growth and insulin use as well as slow appetite and digestion

-glutide
-natide

Don’t confuse with the -ides Sulfonylureas

22
Q

DPP-4 inhibitor class, suffix and MOA?

A

Incretin Acting
-gliptin

Help insulin production in pancreas, reduce blood sugar without hypoglycemia

23
Q

Alpha-glucosidase Inhibitor Class and examples?

A

Oral hypoglycemic

Acarbose
Miglitol

24
Q

Alpha-glucosidase Inhibitor MOA and time taken?

A

Before a meal- help break down starchy foods and sugars

25
Q

Two types of diabetes drugs that are novel oral hypoglycemics?

A

Meglitinides
Sodium Glucose Transporter (SGLT) 2 Inhibitors

26
Q

What do Meglitinide do and suffix?

A

Help body release insulin

-glinide

27
Q

What do you have to be careful about with Meglitinides?

A

Lowering the blood sugar too much

28
Q

How do Sodium Glucose Transporter (SGLT) 2 Inhibitors work?

Suffix?

A

Prevent the kidneys from holding on to glucose- pee in out!

-glifozin