Hypertension Flashcards
Wha are the 4 main types of Primary Hypertension therapeutic agents.
ACEi, ARBs, CCBs, Diuretics (Thiazides-Likes)
Name 2 ACEi
Ramipril, Lisinopril
Side Effects of ACEi
Hypotension, Dry Cough(BK), Hyperkalaemia, Renal Failure, Angioedema.
Contraindications of ACEi + Drug Interactions
Renal Artery Stenosis, AKD+CKD, Pregnancy, Breastfeeding
Drugs that ↑K+, NSAIDs, Other Antihypertensives.
Name 2 ARBs
Candesartan, Losartan
Contraindications of ARBs
Renal Artery Stenosis, AKD+CKD, Pregnancy, Breastfeeding
Drug Interactions of ARBs
Drugs that ↑K+, NSAIDs, Other Antihypertensives
Name 3 CCBs for Hypertension
Amlodipine, Nifedipine, Nimodopine,
Side Effects of Dihydropyridine CCBs
Ankle Swelling, Flushing, Headaches(due to vasodilation), Palpitations(due to compensatory tachycardia due to vasodilation)
Contraindications of Dihydropyridine CCBs
Unstable Angina, Severe Aortic Stenosis
Drug Interactions of Dihydropyridine CCBs
Amlodipine + Statins = Increased Statin Effects, Other Antihypertensives.
Name a Thiazide-like diuretic for Hypertension
Indapamide
Side Effects of Thiazide-like
Hypokalaemia, Hyponatremia, Hyperuricemia, Arrhythmias, ↑Glucose, ↑Cholesterol
Contraindications of Thiazide-like
Hypokalaemia, Gout, Hyponatremia
Drug Interactions of Thiazide-like
Drugs that ↓ K+, NSAIDs
What Antihypertenstives to give patients with T2 DM + Why
ACEi/ARBs. Because of their dilation of EA + ↓Intraglomerular Pressure which means ↓proteinuria
Drugs to give in resistant (stage 4) hypertension
Spironolactone, BBlockers (Labetalol, Bisprolol,Metoprolol), ABlockers (doxazosin)
What is first-line drug for Chronic HF
Diuretic - Furosemide
What drugs to give in HF with reduced EF
Offer ACEi and BB
What is the 1st line drug for treating Primary Hypertension in patients with out T2 DM
Offer CCB
2nd line is CCB + ACEi/ARB
