Hypertension Flashcards

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1
Q

Wha are the 4 main types of Primary Hypertension therapeutic agents.

A

ACEi, ARBs, CCBs, Diuretics (Thiazides-Likes)

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2
Q

Name 2 ACEi

A

Ramipril, Lisinopril

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3
Q

Side Effects of ACEi

A

Hypotension, Dry Cough(BK), Hyperkalaemia, Renal Failure, Angioedema.

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4
Q

Contraindications of ACEi + Drug Interactions

A

Renal Artery Stenosis, AKD+CKD, Pregnancy, Breastfeeding

Drugs that ↑K+, NSAIDs, Other Antihypertensives.

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5
Q

Name 2 ARBs

A

Candesartan, Losartan

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6
Q

Contraindications of ARBs

A

Renal Artery Stenosis, AKD+CKD, Pregnancy, Breastfeeding

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7
Q

Drug Interactions of ARBs

A

Drugs that ↑K+, NSAIDs, Other Antihypertensives

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8
Q

Name 3 CCBs for Hypertension

A

Amlodipine, Nifedipine, Nimodopine,

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9
Q

Side Effects of Dihydropyridine CCBs

A

Ankle Swelling, Flushing, Headaches(due to vasodilation), Palpitations(due to compensatory tachycardia due to vasodilation)

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10
Q

Contraindications of Dihydropyridine CCBs

A

Unstable Angina, Severe Aortic Stenosis

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11
Q

Drug Interactions of Dihydropyridine CCBs

A

Amlodipine + Statins = Increased Statin Effects, Other Antihypertensives.

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12
Q

Name a Thiazide-like diuretic for Hypertension

A

Indapamide

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13
Q

Side Effects of Thiazide-like

A

Hypokalaemia, Hyponatremia, Hyperuricemia, Arrhythmias, ↑Glucose, ↑Cholesterol

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14
Q

Contraindications of Thiazide-like

A

Hypokalaemia, Gout, Hyponatremia

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15
Q

Drug Interactions of Thiazide-like

A

Drugs that ↓ K+, NSAIDs

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16
Q

What Antihypertenstives to give patients with T2 DM + Why

A

ACEi/ARBs. Because of their dilation of EA + ↓Intraglomerular Pressure which means ↓proteinuria

17
Q

Drugs to give in resistant (stage 4) hypertension

A

Spironolactone, BBlockers (Labetalol, Bisprolol,Metoprolol), ABlockers (doxazosin)

18
Q

What is first-line drug for Chronic HF

A

Diuretic - Furosemide

19
Q

What drugs to give in HF with reduced EF

A

Offer ACEi and BB

20
Q

What is the 1st line drug for treating Primary Hypertension in patients with out T2 DM

A

Offer CCB

2nd line is CCB + ACEi/ARB