Hypertension Flashcards
True or False: Men generally have higher blood pressure in younger populations but after age 65 women generally have higher blood pressure.
True
What are common diseases attributed with hypertension?
heart failure stroke retinopathy aortic aneurysm PVD myocardial infarction coronary heart disease kidney failure
What is the leading factor for CVD mortality?
hypertension
In pts in the 25-79 age group what can every 10% increase in hypertension treatment prevent?
an additional 14,000 deaths per year
True or false: nearly 2 in every 5 patients that have a mobility limitation also have HTN
True
Roughly what percentage of home health pt population has pre-HTN or HTN measurements? How many have a known diagnosis of HTN?
75%
43%
What is the fastest system in the body that regulates blood pressure?
Baroreceptors (aortic arch and carotid sinuses)
What are the slower systems in the body that regulate blood pressure?
Renin-Angiotensin System (kidneys)
Natriuretic peptides (ANP and BNP in the heart)-acts as a counter to RAAS system
What is the role of norepinephrine for regulation of arterial blood flow?
responds to sympathetic neural activity to redistribute blood to areas of need
-released by arterioles and attaches to alpha-1 receptors and causes VASOCONSTRICTION
How do you calculate cardiac output?
heart rate x stroke volume
What is the typical range of mean arterial pressure?
85-100 mmHg in adults
What do baroreceptors respond to?
stretching of the arterial wall and forms a negative feedback loop with the vagus and glossopharyngeal nerves
Are aortic arch receptors more or less sensitive than carotid sinus receptors?
Less sensitive
carotid sinus responds to pressures ranging from 60-180 mmHg and aortic arch receptors have a higher threshold pressure
How do Baroreflexors regulate arterial pressure?
- Arterial pressure decreases
- decreased baroreceptor firing
- increases sympathetic activity in medulla
- Increases cardiac output and stroke volume
- increases arterial pressure
What stimulates release of Renin from the kidneys?
- sympathetic nerve activation
- renal artery hypotension
- decreased sodium delivery to the distal tubules of the kidney
How does Renin effect blood pressure?
- Renin released from kidney
- Renin turns angiotensinogen to angiotensin 1
- ACE turns angiotensin 1 to angiotensin 2
- angiotensin 2 causes arteriole vasoconstriction/increased sympathetic activity/ADH secretion (which retains water and increases BP)
What is essential and secondary hypertension?
Essential- accounts for 95-99% of cases and is the interaction between environmental factors and genetics
Secondary-accounts for 1-5% of cases and is the result of some biochemical or mechanical pathology, potentially reversible
What are common contributors for hypertension?
- diet
- inactivity
- obesity
- abnormalities of adrenal cortex
- sleep apnea
- kidney disease
- symp. nervous syst. activity
- congenital vascular disorders
- recreational drugs and alcohol