Hypertension Flashcards
1
Q
Pre-eclampsia definition
A
> 20 weeks gestation SBP >140, DBP >90
2
Q
Severe pre-eclampsia
A
SBP >160, DBP >110
3
Q
Associated
A
Proteinuria >0.03g/24 hours Renal function >90 Oliguria RUQ tenderness and deranged lFTs Neuro-seizures, clonus and hyperreflexia, persistent visual change + headache
4
Q
Risk for PET
A
Previous hx of PET>diabetes>overweight>autoimmune disease>underlying renal disease
Nulliparity, multiple kids, family hx, age >40
5
Q
CHIPS trial
A
tight control of BP has no detriment to fetal health
6
Q
Meds to use
A
Methyldopa (central), labetalol, nefidipine, hydralazine
7
Q
30% of preclampsia can occur post delivery
A
Post pregnancy, increased risk of CVS effects
8
Q
SFLT (soluble FLT1) is released in pre-eclampsi
A
SLFT1 is a receptor for VEGF and PLGF, thus reducing angiogenesis cell proliferation etc
