Hypertension Flashcards
Hypertension
SBP >140mmHg
DBP >90mmHg
Based on the average of at least 3 readings
Prehypertensive
120-139 and/or 80-89
Stage 1 Hypertension
140-159 and /or 90-99
Stage 2 Hypertension
> 160 and/or >100
Hypertension is called
“the silent killer”
-The WHO identifies it as being responsible for 62% of
cerebrovascular disease and 49% of ischemic heart disease
-CDC estimates that approximately 1 in 4 adults are
hypertensive. Many do not realize
What is blood pressure?
-The force exerted against the walls of the arteries and
veins by the blood as it’s being pumped from the heart
-it’s also the pressure exerted by the walls of the arteries and veins against the blood.
Systolic Pressure
highest amount of pressure
exerted on the arterial wall at the peak of ventricular contraction
Diastolic Pressure
lowest pressure exerted during ventricular relaxation
Mean Arterial Pressure
- average amount of pressure exerted throughout cardiac cycle.
- MAP=1/3(SBP+2DBP)
How is BP Controlled/Maintained?
-Sympathetic Nervous System – Baroreceptors in the carotid arteries can activate SNS.
-Vascular Endothelium – produces several vasoactive
substances.
-Renal System- 1.Controls extracellular fluid.
2.Renin, angiotensin, aldosterone system 3.Prostaglandins - vasodilators.
Primary HTN
Elevated BP without a single
identified cause.
Secondary HTN
Elevated BP with specific cause
which can be identified and corrected.
Preeclampsia
Elevated BP during pregnancy, usually
after 20 weeks. Possible organ damage especially kidneys. Very dangerou
Contributing factors of HTN (primary)
- Elevated SNS activity.
- Elevated sodium retaining/vasocaonstricting hormones. -Increased body weight.
- Diabetes.
- Tobacco/alcohol consumption.
Risk Factors (primary)
- Age
- Body Weight
- Diet
- Exercise
- Genetics
- Sex
- Ethnicity/Socioeconomics
- Alcohol/Tobacco
- Stress
Manifestations of HTN (primary)
- Early on, asymptomatic. Only high BP.
- Headache
- Nocturia
- Mental status changes later on.
- Nausea, vomitting.
- Visual changes, Papilledema(swelling of optic nerve)
Secondary HTN
-Coarctation or congenital narrowing of aorta.
-Side effect of drugs or hormones (ex. Corticosteroids,
estrogen)
-Traumatic brain injury, tumors.
-Glomerulonephritis, kidney disease.
-Cirrhosis
HTN Crisis Manifestations
-Encephalopathy – increased cerebral capillary permeability. -Headache -Nausea, vomitting -Seizures, confusion, coma -Renal insuffieciency -Angina, MI, chest pain, SOB
Nitroprusside sodium
vasodilator given IV in HTN
crisis, must be closely monitored and tightly titrated.
Labetalol
mixed alpha and beta adrenergic blocker
given IV.
Prevention/Treatment
-Modify diet
-Increase activity/exercise, decrease weight
-Stress reduction
-Diet-Dash Diet
Drugs- Vasodilators, diuretics, ACE inhibitors, alpha-
adrenergic blockers, beta adrenergic blockers, calcium channel blockers
-Will depend on individual and the cause(s) of their
HTN
Dash Diet (Dietary Approaches to Stop Hypertension)
-Lots of fruits, vegetables, whole grains, low fat dairy,
fish, poultry, nuts
-Very few sugary foods, sugary beverages, red meats,
added fats
Beta Adrenergic Receptor Blockers
e.g. atenolol,
metoprolol
-Make the heart beat slower and with less force
Angiotensin Converting Enzyme Inhibitors
e.g. enalapril,
lisinopril
-Stops veins from vasoconstricting
Diuretics
e. g. furosemide, hydrochlorothiazide
- Makes you pee
- Potassium sparing -spironolactone