Hypertension Flashcards
Hypertension is defined as sustained systolic BP >_ mmHg
130
Hypertension is defined as sustained diastolic BP >_ mmHg
80
Isolated systolic HTN is defined as systolic BP greater than _ and diastolic BP less than _
130
80
Isolated diastolic HTN is defined as systolic BP less than _ and diastolic BP greater than _
130
80
What is the difference between Stage I and Stage II HTN
Stage I:
SBP 130-139
DBP 80-89
Stage II
SBP >140
DBP >90
What is defined as normal blood pressure?
SBP < 120
DBP < 80
What is defined as elevated blood pressure?
SBP 120-129
DBP < 80
Which population is most affected by HTN?
African Americans (40%)
HTN is a risk factor for what three conditions?
Cardiovascular disease
Stroke
Renal disease
What causes Primary (Essential) HTN?
Etiology is unclear
What contributes to Primary (Essential) HTN?
SNS activity
Dysregulation of RAAS
Deficiency in endogenous vasodilators
What genetic and lifestyle risk factors contribute to HTN?
Obesity
ETOH
Tobacco
What five conditions contribute to Secondary HTN in middle-aged adults?
Hyperaldosteronism
Thyroid dysfunction
OSA
Cushing’s disease
Pheochromocytoma
What are some causes of Secondary HTN in children?
Renal parenchymal disease
Coarctation of the aorta
What age group has the highest percentage of HTN?
Children (70-85%)
Describe Resistant HTN
BP above goal despite 3+ anti-HTN drugs at max dose
(CCB, ACI-I or ARB + diuretic)
Describe Controlled Resistant HTN
Controlled BP requiring 4+ medications
Described Refractory HTN
Uncontrolled BP on 5+ drugs
What is Pseudo-resistant HTN?
Intolerance to medications
Resulting in BP inaccuracies or med noncompliance
(White coat syndrome)
For every _ kg of weight loss we can expect a _ mmHg drop in blood pressure
1
1
What consequences come with Chronic HTN?
Remodeling of small & large arteries
Endothelial dysfunction
Irreversible end-organ damage
What 4 drug classes are effective in treating HTN in Non-black patients?
ACE-I’s
ARBs
CCBs
Thiazide diuretics
What drug classes are effective in black patients w/o HF or CKD initially?
CCBs
Thiazide diuretics
What two drug classes are effective in patients with CKD?
ACE-I’s
ARBs