Hypertension Flashcards
Steps of hypertension treatment
- lifestyle
- drugs
- modify drugs
- more drugs or diuretic added
Math equations
CO= HR x SV
MAP= CO x PVR
ACE inhibitors
(-PRIL) catopril, enalapril, ramipril, benazepril
Complications of ACE inhibitors
cough, angioedema
Ace inhibitor special stuff
watch out for hyperkalemia, NSAIDS decrease effect
ARB drugs(angiotensin II receptor blocker)
(-SARTAN) Losartan, irbesartan, olemasartan, valsartan, azilsartan
ARB special stuff
watch out for lithium toxicity
opposite aldosterone
Aldosterone agonist drugs
(-one) eplerenone, spironolactone
Aldosterone agonist special stuff
watch out for
hyperkalemia(salt substitutions)
lithium toxicity
orthostatic hypotension(diuretics)
Direct Renin inhibitor drugs
Aliskiren
Direct Renin inhibitor complications
angioedema, diarrhea, no pregnancy
Direct Renin inhibitor special stuff
Furosemide decreased effects
increased effect HTN meds
Increased effect statin
decrease absorption high fat foods
Calcium channel blockers
(-PINE) nifedipine, nicardipine, amlodipine, diltiazem, verapamil
Calcium channel blockers complications
V&D: peripheral edema, bradycardia
Calcium channel blockers special stuff
NO: beta blockers, grapefruit juice
Alpha adrenergic blocker drugs (sympatholytic)
(-ZOSIN) prazosin, doxazosin, terzosin
Alpha adrenergic blocker special stuff
hypotension with other HTN meds
Centrally acting Alpha 2 agonist drugs
Clonidine, guafacine, methyldopa
Centrally acting Alpha 2 agonist complications
drowsiness, sedation, dry mouth, rebound hypertension if stopped abruptly, CNS depression
Centrally acting Alpha 2 agonist special stuff
no alcohol, no pregnant
Cardioselective Beta blocker drugs (sympatholytics)
Cardiac only
(MAE)Beta 1: metoprolol, atenolol, esmolol
Nonselective Beta blocker drugs (sympatholytics)
Cardiac and pulmonary
Beta 1&2: propanolol, nadolol
Alpha and Beta blocker drugs (sympatholytics)
A & B: carvedilol, labetolol
Beta 2 blocker special stuff
(LOL)
no diabetes, pregnancy, athsma
Diuretics drugs first line
Thiazide(first choice): chlorothiazide, hydrochlorothiazide, methyclothiazide, metolazone
Diuretics drugs non first choice
amiloride, spironolactone, triamterene
Hypertensive crisis meds
Nitro prusside (first choice), nitroglycerin, nicardipine, clevdipine, enalaprit, esmolol, labetolol
Hypertensive crisis meds special stuff
no other IV meds at same time
Hypotension drugs
Midodrine, droxidopa(orthostatic hypotension), vasopressors, adrenergic agonists