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MG: circulatory tract > Hypertension > Flashcards

Hypertension Flashcards

1
Q

Enalapril

A

ACE inhibitor

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2
Q

ACE inhibitors indications

A

Congestive heart failure, arterial hypertension, myocardial infarction, chronic kidney failure

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3
Q

Candesartan

A

Angiotensin 2 receptor blocker (ARB)

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4
Q

Ibesartan

A

Angiotensin 2 receptor blocker (ARB)

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5
Q

Valsartan

A

Angiotensin 2 receptor blocker (ARB)

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6
Q

Olmesartan

A

Angiotensin 2 receptor blocker (ARB)

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7
Q

Nifedipine

A

Inhibit the vascular L-type calcium channels by binding to the alpha1 subunit.

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8
Q

ARBs indication

A

Congestive heart failure, arterial hypertension, myocardial infarction, chronic kidney failure

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9
Q

Amlodipine

A

Inhibit the vascular L-type calcium channels by binding to the alpha1 subunit.

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10
Q

Dihydropyridines indications

A

Arterial hypertension, prinzmetal’s vasospastic angina, Raynaud’s syndrome, chronic stable angina (amlodipine), hypertensive emergency (nifedipine)

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11
Q

Verapamil

A

A phenylalkylamine. Inhibition of the cardiac L type calcium channels by binding to the alpha1-subunit.

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12
Q

Gallopamil

A

A phenylalkylamine. Inhibition of the cardiac L type calcium channels by binding to the alpha1-subunit.

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13
Q

Diltiazem

A

Inhibit both the vascular and cardiac L-type calcium channels.

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14
Q

Phenylalkylamine indications

A

arterial hypertension, coronary sclerosis dependent angina, supraventricular tachyarrhythmia

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15
Q

Diltiazem indications

A

Arterial hypertonicity, coronary sclerosis-dependent angina, vasospastic angina, supraventricular tachyarrhythmia

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16
Q

Atenolol

A

Selective beta1-receptor blocker

17
Q

Metoprolol

A

Selective beta1 receptor blocker

18
Q

Propanolol

A

Beta receptor blocker

19
Q

Beta blockers indication

A

Arterial hypertonicity
Sinus tachycardia
Atrial fibrillation
Supraventricular tachycardia
Following a myocardial infarction
Angina pectoris

20
Q

Bosartan

A

Endothelin receptor antagonist. Prevents the interaction of endothelin and its receptor, preventing the calcium release into the SMC.

21
Q

Ambrisentan

A

Endothelin receptor antagonist.

22
Q

Macitentan

A

Endothelin receptor antagonist.

23
Q

Endothelin receptor antagonist indication

A

Pulmonary hypertension

24
Q

Riociguat

A

Guanylate stimulator. Increases the cGMP and thereby reduces the calcium levels (induces relaxation)

25
Q

Sildenafil

A

Phosphodiesterase 5 inhibitor. cAMP can no longer be broken down

26
Q

Tadalafil

A

Phosphodiesterase 5 inhibitor. cAMP can no longer be broken down

27
Q

PDE5 inhibitors indication

A

Pulmonary hypertension

28
Q

Iloprost

A

Prostaglandin 1 analogue.
Directly activate prostaglandin receptor and thereby enhances the cAMP signaling, reduces calcium and causes relaxation of the SMC.

29
Q

Alpostadil

A

PGE1 analogue.
Directly activate prostaglandin receptor and thereby enhances the cAMP signaling, reduces calcium and causes relaxation of the SMC.

30
Q

Prostaglandin analogues indications

A

Pulmonary hypertension
Arterial obstruction

31
Q

Selexipag

A

Prostacyclin IP receptor (PGI2) agonist. Causes the upregulation of cAMP and thereby reducing the calcium levels. Relaxation is induced.

MG: circulatory tract (3 decks)

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