Hypersensitvity Reactions Flashcards
1
Q
Type 1
A
A
Anaphylactic (immediate)
Rapid 15-30
Bronchial asthma, bee sting, hay fever
IgE, mast cell, basophils
2
Q
Type 2
C
A
Cytotoxic
Mins to hours
Goodpasteur’s (lung + kidney),Blood transfusions ,Myasthenia gravis
IgG,
3
Q
Type 3
I
A
Immune complex mediated
3-10 hours
Glomeruloneohritis, lupus, RA, local necrosis, serum sickness=systemic
IgG & complement
4
Q
Type 4
D
A
Delayed hyper sensitivity Aka cell mediated aka cellular 48 hours TB, contact dermatitis, transplant rejection via MHC T cell Lymphocytes