Hypersensitivity Reactions Flashcards
What immunoglobulin are type 1 hypersensitivity reactions mediated by?
IgE
What are three examples of a type 1 hypersensitivity reaction?
Insect bite
Penicillin allergy
Asthma
Will also accept:
Eczema
Food allergy
Anaphylactic shock
What mediates a type 2 hypersensitivity reaction?
Cytotoxic IgG or IgM
What are three examples of a type 2 hypersensitivity reaction?
Haemolytic anaemia
Hyperacute organ rejection
Goodpastures syndrome (anti-glomerular basement membrane disease)
What mediates a type 3 hypersensitivity reaction?
Immune complex IgM or IgG
What are 3 examples of a type 3 hypersensitivity reaction?
Hypersensitivity pneumonitis (e.g bird fanciers lung)
SLE
RA
Also accept:
Post-streptococcal glomerulonephritis
What mediates a type 4 hypersensitivity reaction?
Cell mediated (T cells)
What are 3 examples of a type 4 hypersensitivity reaction?
Contact dermatitis
T1DM
Multiple sclerosis