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Immunity > Hypersensitivity Reactions > Flashcards

Hypersensitivity Reactions Flashcards

1
Q

What is the definition of hypersensitivity?

A

Antigen-specific immune response that are either inappropriate or excessive, and result in harm to host

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2
Q

What types of antigens can cause hypersensitivity reactions?

A

Exogenous antigens

Intrinsic antigens

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3
Q

What are the types of hypersensitivity reactions?

A

Type I - Allergy
Type II - antiBody mediated
Type III - immune Complex mediated
Type IV - Delayed

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4
Q

Which type of hypersensitivity reactions are antibody related?

A

Type I
Type II
Type III

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5
Q

Which hypersensitivity reaction involves IgE?

A

Type I

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6
Q

Which hypersensitivity reactions involve IgM or IgG?

A

Type II

Type III

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7
Q

What is the sensitisation phase of a hypersensitivity reaction?

A

First encounter with the antigen

Activation of APCs and memory effector cells

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8
Q

What is the effector phase of a hypersensitivity reaction?

A

Pathological reaction upon re-exposure to the same antigen

Activates memory cells

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Immunity (5 decks)

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