Hypersensitivity DDC Rolainne Flashcards
Allergic reactions
Hypersensitivity
2 types of hypersensitivity
Immediate hypersensitivity reaction
Delayed hypersensitivity reaction
Classification of allergic reaction
Hypersensitivity I
Hypersensitivity II
Hypersensitivity III
Hypersensitivity IV
Also known as anaphylactic reaction
Hypersensitivity type I
what type of reaction is considered immediate type
Hypersensitivity type I and II
Reaction of the body wherein causes circulatory shock and may be fatal. Can be manifested after exposure to an allergen/antigen considered by the body as foregin
Hypersensitivity type I
Food allergen (shrimps)
Hypersensitivity type I
Some medications (ex.penicilin)
Hypersensitivity type I
Pollens, plants (poison ivy)
Hypersensitivity type I
Odors chemicals etc
Hypersensitivity type I
Known as cytotoxic reaction
Hypersensitivity type II
Body mechanism that reacts via its defense mechanism however might cause high mortality if not manage early
Hypersensitivity type II
condition can be manifested as a serum sickness as seen in non compatible transfusion of blood and or its components proteins causes massive cellular hemolysis
Hypersensitivity type II
Causes massive cellular hemolysis
Hypersensitivity type II
These is an immunological reaction where in the body’s antibodies reacts to destroy its own tissue
Hypersensitivity type III
This allergic reaction is considered as delayed type because the bodys 3rd line of defense creates first an antibody towards the material as presented to be an antigen
Hypersensitivity type III
A consequence of post infectious with beta hemolytic streptococci causing acute tonsilo-pharyngitis
Hypersensitivity type III
Known as antibody-antigen rxn
Hypersensitivity type III
It produces a toxin and introduced to the 3rd line of defense in turn it produces antibodies against it but it causes a violent reaction to tissue destruction
Hypersensitivity type III
Tissue destruction
Hypersensitivity type III
Rheumatic heart disease (RHD)
Hypersensitivity type III
Glomerulo nephritis (GN) destruction of kidneys
Hypersensitivity type III
Systemic lupus erythmatusus (SLE)
Myasthenia gravis (MG)
An immune reaction considered also as delayed type of reaction
Hypersensitivity type IV
Graft rejection reaction
Hypersensitivity type IV
The body’s own antibodies reacts to destroy a foreign material which a transplanted material has an identifiable antigen > HLA (human lymphocytic antigen
Hypersensitivity type IV
Recognize by owns antibodies especially immune system “killer cells”
Hypersensitivity type IV
Cytotoxic cells
Lymphocytes (B and T)
Immunoglobulins
Hypersensitivity type IV
Skin, mucus membrane
1st line of defense
Stationed phagocytes
1st line of defense
Barriers (secretions)
1st line of defense
Rashes, pigmentation
Warmth or cold skin
1st line of defense
Mobile phagocytes
2nd line of defense
White blood cells
2nd line of defense
Leukocytes
2nd line of defense
Increase eosinophils leukocytosis
(+) histamine
2nd line of defense
Immune system
3rd line of defense
Immunoglobulins
3rd line of defense
Killer cells (t-lymphocytes)
3rd line of defense
Increase immunoglobulin E resolution
3rd line of defense
2 types of immunity
Innate immunity
Adaptive immunity
Ability of the body to resist certain infection through its bodily barriers through its first line of defense
Innate immunity
Skin and its protective processes, antibodies acquired from the mother that crosses the placenta
Innate immunity
Ability of the body to resists foreign body or antigen by the capabilities of the immune system to produce specific antibodies to certain antigens by/through sensitization of the immune system
Adaptive immunity
2 classifications of adaptive immunity
Natural immunity
Acquired immunity
Natural passive immunity
Natural immunity
Antibodies received from the mother via crosses placental barrier through mothers milk (colustrums)
Natural passive immunity
2 types of natural immunity
Natural passive immunity
Natural active immunity
Colostrums
Natural passive immunity
Short live immunity
Natural passive immunity
Acquired passive immunity
The body produces its own specific antibodies by acquiring it through the process of getting infected then the immune system produces its own specific antibiotics
Natural active immunity
Infected with chicken pox
Natural active immunity
2 types of acquired immunity
Acquired passive immunity
Acquired active immunity
Antibodies received as immunoglobulins as a vaccine
Acquired passive immunity
Human tetanus immune globulins
Acquired passive immunity
Body receives either live or attenuated antigen/material of a specific bacteria or virus as a form of vaccine the body response to produce own specific antibodies
Acquired active immunity
Immunized with measles vaccine
Acquired active immunity
2 way process of immune system
Humoral response
Cellular response
Antibody production
Humoral response
Immunoglobulin G (IgG)
Humoral response
Seen in 1st exposure to an antigen
Immunoglobulin G (IgG)
Immuneglobulin M (IgM)
Humoral response
Seen w/ 2nd exposure to an antigen
Immuneglobulin M (IgM)
Immuneglobulin A (IgA)
Humoral response
Seen in our bodily secretions
Immuneglobulin A (IgA)
Tears semen mucus membrane
Immuneglobulin A (IgA)
Immuneglobulin D (IgD)
Humoral response
Not clear but seen to increase production of B lymphocytes
Immunoglobulin D (IgD)
Immunoglobulin E (IgE)
Humoral response
Seen to increase with or in cases of hypersensitivity reactions
Immunoglobulin E (IgE)
Produces phagocytic /killer cells
Cellular response
B&T lymphocytes, helper and killer
Cellular response
Cytotoxic cells, NK cells, tumor neutralizing cells
Cellular response
Interferons
Cellular response
Antibodies received through from the mother via crosses placental barrier and through mothers milk
Natural passive immunity