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Principles of Disease > Hypersensitivity and Autoimmunity > Flashcards

Hypersensitivity and Autoimmunity Flashcards

1
Q

What are the two types of immunity

A

Innate and Adaptive

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2
Q

Define hypersensitivity

A

When the normally beneficial components of the immune response act in an exaggerated or inappropriate way to environmental antigens which do not normally cause tissue damage

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3
Q

What is the main way type 1 hypersensitivity arises

A

Inappropriate synthesis of IgE, presence of IgE is associated with allergy

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4
Q

Describe type II hypersensitivity

A

Can be autoimmune

IgE or IgM

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5
Q

Describe type III hypersensitivity

A

Conditions arise as a result of abnormal deposition of formed antigen

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6
Q

Describe type IV hypersensitivity

A

No detectible antibody component

Mediated by Th1 cells and cytokine products

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7
Q

Define autoimmune disease

A

A clinical disorder characterised by tissue or organ damage mediated through immunological mechanisms which are directed against self antigens

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Principles of Disease (5 decks)

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